5,6-epoxycyclooctene

Base Information

• Chemical Name: 5,6-epoxycyclooctene
• CAS No.: 73176-71-3
• Molecular Formula: C₈H₁₂O
• Molecular Weight: 124.183
• Mol file: 73176-71-3.mol

Synonyms:

Chemical Property of 5,6-epoxycyclooctene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5,6-epoxycyclooctene

There total 21 articles about 5,6-epoxycyclooctene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1,5-cis,cis-cyclooctadiene (1552-12-1,111-78-4) → (Z)-9-oxabicyclo[6.1.0]non-4-ene (19740-90-0,57378-34-4,65207-47-8,73176-71-3,73176-86-0,117468-08-3,637-90-1)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; chloroform; at 20 ℃; for 18h;

DOI:10.1021/ma051709z

Reference yield: 89.0%

cyclo-octa-1,5-diene (5259-72-3,10060-40-9,111-78-4) → 5,6-epoxycyclooctene (73176-71-3,637-90-1,73176-86-0,1225194-35-3,1225194-65-9)

Guidance literature:

With tert.-butylhydroperoxide; at 90 ℃; for 10h;

DOI:10.1016/j.apcata.2013.06.012

Reference yield: 86.7%

cyclo-octa-1,5-diene (5259-72-3,10060-40-9,111-78-4) → 1,2:5,6-diepoxycyclooctane (286-75-9,19740-81-9,57378-35-5) + 5,6-epoxycyclooctene (73176-71-3,637-90-1,73176-86-0,1225194-35-3,1225194-65-9)

Guidance literature:

With C₃₀H₂₅ClCoN₃OP; dihydrogen peroxide; 1-ethyl-3-methylimidazolium hexafluorophosphate; In water; at 20 ℃; for 2h; Green chemistry;

DOI:10.1016/j.crci.2013.12.004

upstream raw materials:

1,5-cis,cis-cyclooctadiene

Trans-2-fluorocyclooct-5-en-1-ol

trans-8-iodo-cyclooct-4-en-1-yl acetate

cyclo-octa-1,5-diene

Downstream raw materials:

(Z)-8-(benzylamino)cyclooct-4-enol

Cyclooctene oxide

Cyclooctan

rac-(Z)-cyclooct-5-en-1,2-diol