3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%

Base Information

Chemical Name:3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%
CAS No.:84163-10-0
Molecular Formula:C14H15 F N2 O2
Molecular Weight:262.284
Hs Code.:
Mol file:84163-10-0.mol

Synonyms:Piperidine,1-acetyl-4-(5-fluoro-1,2-benzisoxazol-3-yl)- (9CI); 1,2-Benzisoxazole,piperidine deriv.

Suppliers and Price of 3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-(5-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethanone 95+%
10g
$ 425.00

Alfa Aesar
3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%
1g
$ 138.00

Alfa Aesar
3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%
250mg
$ 49.80

Total 9 raw suppliers

Chemical Property of 3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%

Chemical Property:

Melting Point:158-159℃
PSA：46.34000
LogP:2.63070
Storage Temp.:-20°C Freezer
Solubility.:Chloroform (Slightly), Methanol (Slightly)

Purity/Quality:

NLT 98% ^*data from raw suppliers

1-(4-(5-Fluorobenzo[d]isoxazol-3-yl)piperidin-1-yl)ethanone 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-[4-(5-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethanone is used as a reagent in the synthesis of a series of 3-(1-substituted-4-piperidinyl)-1,2-benzisoxazoles which exhibit neuroleptic activity.

Technology Process of 3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96%

There total 3 articles about 3-(1-Acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole, 96% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 84163-52-0,84163-76-8
C₁₆H₁₉FN₂O₄

: 84163-10-0
3-(1-acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; for 16h; Yield given; Ambient temperature;
DOI:10.1021/jm00383a012

Reference yield:

: 84162-97-0,84163-60-0
1-acetyl-4-(5-fluoro-2-hydroxybenzoyl)piperidine oxime

: 84163-10-0
3-(1-acetyl-4-piperidinyl)-5-fluoro-1,2-benzisoxazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.5 h / 60 °C

2: NaH / dimethylformamide / 16 h / Ambient temperature

With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1021/jm00383a012