Technology Process of C18H21N5OS
There total 4 articles about C18H21N5OS which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
water; toluene;
at 60 ℃;
Inert atmosphere;
Schlenk technique;
DOI:10.1021/jo301059u
- Guidance literature:
-
Multi-step reaction with 4 steps
1: water; toluene; tetrahydrofuran; hexane / Inert atmosphere; Schlenk technique; Reflux
2: hydrogenchloride; water / dichloromethane; ethanol; methanol / 12 h / 20 °C / Inert atmosphere; Schlenk technique
3: Iodine monochloride / methanol; N,N-dimethyl-formamide / 20 °C / Inert atmosphere; Schlenk technique
4: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; toluene / 60 °C / Inert atmosphere; Schlenk technique
With
hydrogenchloride; tetrakis(triphenylphosphine) palladium(0); water; Iodine monochloride; potassium carbonate;
In
tetrahydrofuran; methanol; ethanol; hexane; dichloromethane; water; N,N-dimethyl-formamide; toluene;
4: |Suzuki Coupling;
DOI:10.1021/jo301059u
- Guidance literature:
-
Multi-step reaction with 2 steps
1: Iodine monochloride / methanol; N,N-dimethyl-formamide / 20 °C / Inert atmosphere; Schlenk technique
2: potassium carbonate; tetrakis(triphenylphosphine) palladium(0) / water; toluene / 60 °C / Inert atmosphere; Schlenk technique
With
tetrakis(triphenylphosphine) palladium(0); Iodine monochloride; potassium carbonate;
In
methanol; water; N,N-dimethyl-formamide; toluene;
2: |Suzuki Coupling;
DOI:10.1021/jo301059u
