1-methyl-1H-pyrazol-4-amine hydrochloride

Base Information

• Chemical Name: 1-methyl-1H-pyrazol-4-amine hydrochloride
• CAS No.: 127107-23-7
• Molecular Formula: C4H7N3
• Molecular Weight: 133.581
• Hs Code.: 2933199090
• European Community (EC) Number: 812-317-9
• Mol file: 127107-23-7.mol

Synonyms:1-methyl-1H-pyrazol-4-amine hydrochloride;127107-23-7;4-Amino-1-methylpyrazole Hydrochloride;1-Methyl-1H-pyrazol-4-ylamine hydrochloride;1-METHYL-1H-PYRAZOL-4-AMINE HCL;1-methylpyrazol-4-amine hydrochloride;1-methylpyrazol-4-amine;hydrochloride;1-Methylpyrazol-4-amine HCl;1H-Pyrazol-4-amine, 1-methyl-, hydrochloride (1:1);1-Methyl-1H-pyrazol-4-ylamine HCl;MFCD07626616;SCHEMBL186146;OKPCAONVUKBJJQ-UHFFFAOYSA-N;AMY10788;CS-D1698;AKOS003233994;SB10558;1-methyl-1H-pyrazol-4-aminehydrochloride;DA-16961;DS-13224;SY022073;1-methyl-1H-pyrazole-4-amine hydrochloride;EN300-52973;F2147-0616

Chemical Property of 1-methyl-1H-pyrazol-4-amine hydrochloride

Chemical Property:

• Boiling Point: 231.4 °C at 760 mmHg
• Flash Point: 93.8 °C
• PSA: 43.84000
• Density: 1.22 g/cm³
• LogP: 0.58350
• Storage Temp.: Inert atmosphere,Room Temperature
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 133.0406750
• Heavy Atom Count: 8
• Complexity: 64

Purity/Quality:

97% ^*data from raw suppliers

1-Methyl-1H-pyrazol-4-amineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN1C=C(C=N1)N.Cl

Technology Process of 1-methyl-1H-pyrazol-4-amine hydrochloride

There total 2 articles about 1-methyl-1H-pyrazol-4-amine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C6H9N3O → 1-methyl-1H-pyrazol-4-amine monohydrochloride (127107-23-7,1063734-49-5)

Guidance literature:

With hydrogenchloride; water; In butan-1-ol; at 85 ℃;

DOI:10.1021/acs.oprd.1c00066

Reference yield:

1-methyl-4-aminopyrazole (69843-13-6) → 1-methyl-1H-pyrazol-4-amine monohydrochloride (127107-23-7,1063734-49-5)

Guidance literature:

With hydrogenchloride; In ethanol;

Reference yield: 95.0%

C16H22ClN5OS + 1-methyl-1H-pyrazol-4-amine monohydrochloride (127107-23-7,1063734-49-5) → 2-methyl-N5-(1-methyl-1H-pyrazol-4-yl)-N7-((1r,4r)-4-morpholinocyclohexyl)thiazolo [5,4-d]pyrimidine-5,7-diamine

Guidance literature:

In butan-1-ol; at 110 ℃;

upstream raw materials:

1-methyl-4-aminopyrazole