methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

Base Information

Chemical Name:methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate
CAS No.:958332-63-3
Molecular Formula:C12H7ClF3NO2
Molecular Weight:289.641
Hs Code.:2933499090
Mol file:958332-63-3.mol

Synonyms:Methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate;

Suppliers and Price of methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate 95+%
1g
$ 668.00

Chemenu
methyl4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate 95%
1g
$ 632.00

American Custom Chemicals Corporation
METHYL-4-CHLORO-2-(TRIFLUOROMETHYL)QUINOLINE-6-CARBOXYLATE 95.00%
5MG
$ 496.49

Alichem
Methyl4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate
1g
$ 549.44

Total 15 raw suppliers

Chemical Property of methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

Chemical Property:

Vapor Pressure:0.000465mmHg at 25°C
Refractive Index:1.55
Boiling Point:314.5 °C at 760 mmHg
Flash Point:144 °C
PSA：39.19000
Density:1.447 g/cm³
LogP:3.69360

Purity/Quality:

98%min ^*data from raw suppliers

Methyl4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

There total 2 articles about methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 958332-60-0
methyl 4-hydroxy-2-(trifluoromethyl)quinoline-6-carboxylate

: 958332-63-3
methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

Guidance literature:: methyl 4-hydroxy-2-(trifluoromethyl)quinoline-6-carboxylate; With trichlorophosphate; at 110 ℃; for 20h;

With ammonium hydroxide; In water; Cooling with ice;

With hydrogenchloride; In water; pH=5;

Reference yield:

: 619-45-4
4-methoxycarbonyl aniline

: 958332-63-3
methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: polyphosphoric acid / 125 °C

2.1: trichlorophosphate / 20 h / 110 °C

2.2: Cooling with ice

2.3: pH 5

With trichlorophosphate;

Reference yield:

: 958332-63-3
methyl 4-chloro-2-(trifluoromethyl)quinoline-6-carboxylate

: 108-91-8,157973-60-9
cyclohexylamine

: 4-cyclohexylamino-2-trifluoromethylquinoline-6-carboxylic acid methyl ester

Guidance literature:: With caesium carbonate; palladium diacetate; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; In N,N-dimethyl-formamide; at 120 ℃; for 0.25h; Microwave irradiation;