1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid

Base Information

Chemical Name:1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid
CAS No.:813426-13-0
Molecular Formula:C₁₅H₁₇NO₂
Molecular Weight:243.305
Hs Code.:2933990090
DSSTox Substance ID:DTXSID20461992
Mol file:813426-13-0.mol

Synonyms:813426-13-0;1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid;spiro[1,2,3,5-tetrahydro-1-benzazepine-4,3'-cyclopentene]-1'-carboxylic acid;1,2,3,5-tetrahydro-spiro[4h-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid;Spiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid, 1,2,3,5-tetrahydro-;SCHEMBL4101230;DTXSID20461992;UJGOKTVNHDTZTN-UHFFFAOYSA-N;AKOS015950942;1,2,3,5-tetrahydrospiro[1-benzazepine-4,1'-cyclopent[2]ene]-3'-carboxylic acid;1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1'-[2]cyclopentene]-3'-carboxylic acid;AC-24261;CS-0001976;FT-0646576;A26889;A840106;1'-spiro[1,2,3,5-tetrahydro-1-benzazepine-4,3'-cyclopentene]carboxylic acid;1,2,3,5-tetrahydrospiro[benzo[b]azepine-4,1'-cyclopentan]-2'-ene-3'-carboxylic acid;1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylicacid;Spiro[4h-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylicacid,1,2,3,5-tetrahydro-

Suppliers and Price of 1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylicacid 95+%
1g
$ 1186.00

Chemenu
1,2,3,5-tetrahydrospiro[benzo[b]azepine-4,1''-cyclopentan]-2''-ene-3''-carboxylicacid 95%
1g
$ 1118.00

American Custom Chemicals Corporation
1,2,3,5-TETRAHYDROSPIRO[4H-1-BENZAZEPINE-4,1''-[2]CYCLOPENTENE]-3''-CARBOXYLIC ACID 95.00%
5MG
$ 496.18

Alichem
1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylicacid
1g
$ 1008.00

Total 13 raw suppliers

Chemical Property of 1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid

Chemical Property:

Boiling Point:451.81 °C at 760 mmHg
Flash Point:227.047 °C
PSA：49.33000
Density:1.244 g/cm³
LogP:2.97390
Storage Temp.:2-8°C
XLogP3:3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:243.125928785
Heavy Atom Count:18
Complexity:377

Purity/Quality:

97% ^*data from raw suppliers

1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCNC3=CC=CC=C3C2)C=C1C(=O)O

Technology Process of 1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid

There total 3 articles about 1,2,3,5-Tetrahydrospiro[benzo[b]azepine-4,1-cyclopent[2]ene]-3'-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: (4R)-1,2,3,5-tetrahydro-spiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid (1S)-7,7-dimethyl-2-oxo-bicyclo[2.2.1]heptane-1-methanesulfonic acid salt

: 813426-13-0
(4R)-1,2,3,5-tetrahydrospiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid

Guidance literature:: With sodium hydrogencarbonate; In water; for 1h; pH=6;

Reference yield: 88.0%

: (4R)-1,2,3,5-tetrahydrospiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid*(-)-10-camphorsulfonic acid

: 813426-13-0
(4R)-1,2,3,5-tetrahydrospiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid

Guidance literature:: With sodium hydrogencarbonate; In dichloromethane; water; for 1h; pH=6;

Reference yield:

: 813426-12-9
Ethyl 1,2,3,5-tetrahydro-2'-hydroxy-1-[(4-methylphenyl)sulfonyl]-spiro[4H-1-benzazepine-4,1'-cyclopentane]-3'-carboxylate

: 813426-13-0
1,2,3,5-tetrahydrospiro[4H-1-benzazepine-4,1'-[2]cyclopentene]-3'-carboxylic acid

Guidance literature:: Ethyl 1,2,3,5-tetrahydro-2'-hydroxy-1-[(4-methylphenyl)sulfonyl]-spiro[4H-1-benzazepine-4,1'-cyclopentane]-3'-carboxylate; With sulfuric acid; acetic acid; at 80 - 100 ℃; for 22 - 24h;

With potassium hydroxide; In water; at 10 - 50 ℃; pH=5.5;