(R,R)-o-Tolyl-DIPAMP

Base Information

• Chemical Name: (R,R)-o-Tolyl-DIPAMP
• CAS No.: 810667-85-7
• Molecular Formula: C₂₈H₂₈P₂
• Molecular Weight: 426.478
• Hs Code.: 2919900090
• DSSTox Substance ID: DTXSID90478895
• Mol file: 810667-85-7.mol

Synonyms:(R,R)-o-Tolyl-DIPAMP;(S,S)-o-Tolyl-DIPAMP;(R,R)-1,2-Bis[(2-methylphenyl)(phenyl)phosphino]ethane;1,2-Bis(phenyl(o-tolyl)phosphanyl)ethane;81157-83-7;(S,S)-1,2-Bis[(o-tolyl)(phenylphosphino)]ethane;SCHEMBL4885181;DTXSID90478895;AKOS030245875;(S,S)-(Ethane-1,2-diyl)bis[(2-methylphenyl)phenylphosphane]

Chemical Property of (R,R)-o-Tolyl-DIPAMP

Chemical Property:

• Melting Point: 86-90?°C
• Boiling Point: 543.0±50.0 °C(Predicted)
• XLogP3: 6.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 7
• Exact Mass: 426.16662489
• Heavy Atom Count: 30
• Complexity: 435

Purity/Quality:

99% ^*data from raw suppliers

(S,S)-1,2-Bis[(2-methylphenyl)(phenyl)phosphino]ethane ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1P(CCP(C2=CC=CC=C2)C3=CC=CC=C3C)C4=CC=CC=C4

Technology Process of (R,R)-o-Tolyl-DIPAMP

There total 4 articles about (R,R)-o-Tolyl-DIPAMP which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C18H30B2P2 → (1R,1'R)- 1,1'-(1,2-ethanediyl)bis[1-(2-methylphenyl)-1-phenylphosphine] (1454818-64-4,810667-85-7,81157-83-7,81157-88-2,81157-90-6)

Guidance literature:

With diethylamine; at 15 - 25 ℃; Inert atmosphere;

Reference yield:

(SP)-(2-methylphenyl)methylphenyl phosphine oxide → (1R,1'R)- 1,1'-(1,2-ethanediyl)bis[1-(2-methylphenyl)-1-phenylphosphine] (1454818-64-4,810667-85-7,81157-83-7,81157-88-2,81157-90-6)

Guidance literature:

Multi-step reaction with 4 steps

1.1: toluene / 115 - 125 °C / Inert atmosphere

1.2: 10 - 60 °C / Inert atmosphere

2.1: toluene / 5 - 15 °C / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran / 2 h / -80 - -70 °C / Inert atmosphere

3.2: 1 h / -70 °C

4.1: diethylamine / 15 - 25 °C / Inert atmosphere

With n-butyllithium; diethylamine; In tetrahydrofuran; toluene;

Reference yield:

(S)-methylphenyl(2-tolyl)phosphine (71779-60-7,92621-97-1,73622-07-8) → (1R,1'R)- 1,1'-(1,2-ethanediyl)bis[1-(2-methylphenyl)-1-phenylphosphine] (1454818-64-4,810667-85-7,81157-83-7,81157-88-2,81157-90-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: toluene / 5 - 15 °C / Inert atmosphere

2.1: n-butyllithium / tetrahydrofuran / 2 h / -80 - -70 °C / Inert atmosphere

2.2: 1 h / -70 °C

3.1: diethylamine / 15 - 25 °C / Inert atmosphere

With n-butyllithium; diethylamine; In tetrahydrofuran; toluene;

upstream raw materials:

(S)-methylphenyl(2-tolyl)phosphine

Refernces