tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Base Information

Chemical Name:tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
CAS No.:645418-66-2
Molecular Formula:C16H24N2O2
Molecular Weight:276.379
Hs Code.:2933499090
Mol file:645418-66-2.mol

Synonyms:7-Amino-4,4-dimethyl-3,4-dihydro-1H-isoquinoline-2-carboxylicacid tert-butyl ester;

Suppliers and Price of tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
tert-Butyl7-Amino-4,4-dimethyl-3,4-dihydro-1H-isoquinoline-2-carboxylate 96%
1g
$ 998.00

Chemenu
7-Amino-2-Boc-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline 95%
5g
$ 1777.00

Chemenu
7-Amino-2-Boc-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline 95%
1g
$ 593.00

American Custom Chemicals Corporation
TERT-BUTYL-7-AMINO-4,4-DIMETHYL-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE 95.00%
5MG
$ 497.70

Alichem
tert-Butyl7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
25g
$ 6172.11

Alichem
tert-Butyl7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
10g
$ 3733.80

Alichem
tert-Butyl7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
5g
$ 2286.34

AK Scientific
tert-Butyl7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
1g
$ 1651.00

AK Scientific
tert-Butyl7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
250mg
$ 691.00

Total 21 raw suppliers

Chemical Property of tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.542
Boiling Point:396.795 °C at 760 mmHg
PKA:4.83±0.40(Predicted)
Flash Point:193.775 °C
PSA：55.56000
Density:1.083 g/cm³
LogP:3.81620
Storage Temp.:2-8°C

Purity/Quality:

99%, ^*data from raw suppliers

tert-Butyl7-Amino-4,4-dimethyl-3,4-dihydro-1H-isoquinoline-2-carboxylate 96% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

There total 4 articles about tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 453560-80-0
tert-butyl-4,4-dimethyl-7-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate

: 645418-66-2
tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Guidance literature:: With ammonium chloride; tin(ll) chloride; In ethanol; at 70 ℃; for 1h;

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 645418-66-2
tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water; 1,4-dioxane / 0.08 h / 0 °C

1.2: 2 h / 0 - 20 °C

2.1: tin(ll) chloride; ammonium chloride / ethanol / 1 h / 70 °C

With ammonium chloride; tin(ll) chloride; sodium hydroxide; In 1,4-dioxane; ethanol; water;

Reference yield:

: 442846-93-7
4,4-dimethyl-7-nitro-1,2,3,4-tetrahydroisoquinoline

: 645418-66-2
tert-butyl 7-amino-4,4-dimethyl-3,4-dihydroisoquinoline-2(1H)-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydroxide / water; 1,4-dioxane / 0.08 h / 0 °C

1.2: 2 h / 0 - 20 °C

2.1: tin(ll) chloride; ammonium chloride / ethanol / 1 h / 70 °C

With ammonium chloride; tin(ll) chloride; sodium hydroxide; In 1,4-dioxane; ethanol; water;