2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride

Base Information

Chemical Name:2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride
CAS No.:365996-07-2
Molecular Formula:C6H7BrN2S
Molecular Weight:219.105
Hs Code.:2934999090
DSSTox Substance ID:DTXSID70957870
Mol file:365996-07-2.mol

Synonyms:2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride;949922-52-5;2-bromo-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine hydrochloride;2-bromo-4,5,6,7-tetrahydro-[1,3]thiazolo[5,4-c]pyridine;hydrochloride;2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine, HCl;2-BROMO-4,5,6,7-TETRAHYDRO-THIAZOLO[5,4,-C]PYRIDINE HCL;C6H8BrClN2S;SCHEMBL1019708;DTXSID70957870;PBOWGJGHBQXXET-UHFFFAOYSA-N;AMY33576;AB1197;MFCD08448172;AKOS015843921;SB12339;DS-10819;A859220;J-508256;2-bromo-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine HCl;2-Bromo-4,5,6,7-tetrahydro-thiazolo[5,4,-c]pyridine hydrochloride;2-Bromo-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine;2-BROMO-4,5,6,7-TETRAHYDROTHIAZOLO[5,4-C]PYRIDINE HCL;2-bromo-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine hydrochloride;2-Bromo-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine hydrochloride, AldrichCPR;2-Bromo-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridine--hydrogen chloride (1/1);2-Bromo-4 pound not5 pound not6 pound not7-tetrahydrothiazolo[5 pound not4-c]pyridine hydrochloride

Suppliers and Price of 2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Bromo-4-
100mg
$ 403.00

Usbiological
2-Bromo-4-
50mg
$ 405.00

Usbiological
2-Bromo-4-
250mg
$ 372.00

Matrix Scientific
2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridinehydrochloride >95%
5g
$ 7409.00

Matrix Scientific
2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 95+%
1g
$ 3024.00

Matrix Scientific
2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridinehydrochloride >95%
1g
$ 1853.00

Matrix Scientific
2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 95+%
250mg
$ 1361.00

Crysdot
2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine 95+%
250mg
$ 250.00

Biosynth Carbosynth
2-Bromo-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine
50 mg
$ 704.00

Biosynth Carbosynth
2-Bromo-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine
25 mg
$ 405.00

Total 26 raw suppliers

Chemical Property of 2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride

Chemical Property:

Vapor Pressure:5.79E-05mmHg at 25°C
Boiling Point:341.3°C at 760 mmHg
Flash Point:160.2°C
PSA：53.16000
LogP:2.68210
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:253.92801
Heavy Atom Count:11
Complexity:133

Purity/Quality:

97% ^*data from raw suppliers

2-Bromo-4- ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNCC2=C1N=C(S2)Br.Cl

Technology Process of 2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride

There total 3 articles about 2-Bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 365996-06-1
2-Bromo-5-tert-butoxycarbonyl-4,5,6,7-tetrahydro-thiazolo[5,4-c]pyridine

: 365996-07-2
2-bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine

Guidance literature:: With trifluoroacetic acid; In dichloromethane;
DOI:10.1016/j.bmcl.2011.10.021

Reference yield:

: 79099-07-3
N-tert-butyloxycarbonylpiperidin-4-one

: 365996-07-2
2-bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: pyrrolidine; TsOH*H₂O / cyclohexane / 2 h / Heating

1.2: 63 percent / S₈ / methanol / 5 h / 0 °C

2.1: 49 percent / t-BuONO; CuBr₂ / dimethylformamide / 2 h / 50 - 60 °C

3.1: TFA / CH₂Cl₂ / 0.17 h / 20 °C

With pyrrolidine; tert.-butylnitrite; toluene-4-sulfonic acid; trifluoroacetic acid; copper(ll) bromide; In dichloromethane; cyclohexane; N,N-dimethyl-formamide;
DOI:10.3987/COM-04-10071

Reference yield:

: 365996-05-0
tert-butyl 2-amino-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate

: 365996-07-2
2-bromo-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / t-BuONO; CuBr₂ / dimethylformamide / 2 h / 50 - 60 °C

2: TFA / CH₂Cl₂ / 0.17 h / 20 °C

With tert.-butylnitrite; trifluoroacetic acid; copper(ll) bromide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.3987/COM-04-10071