4-Amino-8-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-erythro-pentofuranosyl]-7(8H)-pteridinone

Base Information

Chemical Name:4-Amino-8-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-erythro-pentofuranosyl]-7(8H)-pteridinone
CAS No.:195442-57-0
Molecular Formula:C₃₂H₃₁N₅O₆
Molecular Weight:581.628
Hs Code.:
DSSTox Substance ID:DTXSID901111590

Synonyms:DTXSID901111590;195442-57-0

Suppliers and Price of 4-Amino-8-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-erythro-pentofuranosyl]-7(8H)-pteridinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Amino-8-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-erythro-pentofuranosyl]-7(8H)-pteridinone

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:9
Exact Mass:581.22743373
Heavy Atom Count:43
Complexity:925

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OCC4C(CC(O4)N5C(=O)C=NC6=C(N=CN=C65)N)O
Isomeric SMILES:COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C(=O)C=NC6=C(N=CN=C65)N)O

Technology Process of 4-Amino-8-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-erythro-pentofuranosyl]-7(8H)-pteridinone

There total 6 articles about 4-Amino-8-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-2-deoxy-beta-D-erythro-pentofuranosyl]-7(8H)-pteridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 187143-64-2
4-Amino-8-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8H-pteridin-7-one

: 195442-57-0
4-Amino-8-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-8H-pteridin-7-one

Guidance literature:: DOI:10.1080/07328319708006188

Reference yield:

: 199789-52-1
4-N,N-dimethylaminomethyleneimino-7(8H)-pteridone

: 195442-57-0
4-Amino-8-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-8H-pteridin-7-one

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / DBU / acetonitrile

2: 88 percent / NH₃

3: 85 percent

With ammonia; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;
DOI:10.1080/07328319708006188

Reference yield:

: 22005-66-9
4-amino-7(8H)-pteridone

: 195442-57-0
4-Amino-8-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-8H-pteridin-7-one

Guidance literature:: Multi-step reaction with 4 steps

2: 54 percent / DBU / acetonitrile

3: 88 percent / NH₃

4: 85 percent

With ammonia; 1,8-diazabicyclo[5.4.0]undec-7-ene; In acetonitrile;
DOI:10.1080/07328319708006188