C₁₄H₂₀N₂O₆

Base Information

• Chemical Name: C₁₄H₂₀N₂O₆
• CAS No.: 136598-16-8
• Molecular Formula: C₁₄H₂₀N₂O₆
• Molecular Weight: 312.323
• Mol file: 136598-16-8.mol

Synonyms:

Chemical Property of C₁₄H₂₀N₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₄H₂₀N₂O₆

There total 7 articles about C₁₄H₂₀N₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-deoxy-2-oxamoylamino-D-mannose → C14H20N2O6 (122623-76-1,134234-43-8,136598-16-8)

Guidance literature:

Multi-step reaction with 6 steps

1: imidazole / dimethylformamide / 6 h / ice-water bath

2: 92 percent / NaBH₄ / methanol / 0.5 h / Ambient temperature

3: 86 percent / BF₃*Et₂O / 4 h / -25 - -18 °C

4: 100 percent / n-Bu₄NF*3H₂O / tetrahydrofuran / 1.5 h / -21 - -17 °C

5: 846 mg / CrO₃, pyridine / CH₂Cl₂ / 0.5 h / Ambient temperature

6: NH₃ / methanol / 20 h / Ambient temperature

With pyridine; 1H-imidazole; chromium(VI) oxide; sodium tetrahydroborate; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; ammonia; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1248/cpb.39.1392

Reference yield:

(2R,3R,4R,5R)-2,3:4,6-di(isopropylidenedioxy)-5-oxamoylaminohexanol (128741-75-3) → C14H20N2O6 (122623-76-1,134234-43-8,136598-16-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 846 mg / CrO₃, pyridine / CH₂Cl₂ / 0.5 h / Ambient temperature

2: NH₃ / methanol / 20 h / Ambient temperature

With pyridine; chromium(VI) oxide; ammonia; In methanol; dichloromethane;

DOI:10.1248/cpb.39.1392

Reference yield:

6-O-tert-Butyldiphenylsilyl-2-deoxy-2-oxamoylamino-D-mannitol (128741-73-1) → C14H20N2O6 (122623-76-1,134234-43-8,136598-16-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 86 percent / BF₃*Et₂O / 4 h / -25 - -18 °C

2: 100 percent / n-Bu₄NF*3H₂O / tetrahydrofuran / 1.5 h / -21 - -17 °C

3: 846 mg / CrO₃, pyridine / CH₂Cl₂ / 0.5 h / Ambient temperature

4: NH₃ / methanol / 20 h / Ambient temperature

With pyridine; chromium(VI) oxide; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; ammonia; In tetrahydrofuran; methanol; dichloromethane;

DOI:10.1248/cpb.39.1392

upstream raw materials:

5-Deoxy-2,3:4,6-di-O-isopropylidene-5-oxamoylamino-D-mannose

(2R,3R,4R,5R)-2,3:4,6-di(isopropylidenedioxy)-5-oxamoylaminohexanol

6-O-tert-Butyldiphenylsilyl-2-deoxy-2-oxamoylamino-D-mannitol

6-O-tert-Butyldiphenylsilyl-2-deoxy-2-oxamoylamino-D-mannose

Downstream raw materials:

8a-epi-kifunensine