3-Chlor-3-phenyl-propyl-ethylether

Base Information

• Chemical Name: 3-Chlor-3-phenyl-propyl-ethylether
• CAS No.: 24491-59-6
• Molecular Formula: C₁₁H₁₅ClO
• Molecular Weight: 198.692
• Mol file: 24491-59-6.mol

Synonyms:

Chemical Property of 3-Chlor-3-phenyl-propyl-ethylether

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-Chlor-3-phenyl-propyl-ethylether

There total 1 articles about 3-Chlor-3-phenyl-propyl-ethylether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + ethyl chloromethyl ether (3188-13-4) → 3-Chlor-3-phenyl-propyl-ethylether (24491-59-6)

Guidance literature:

With zinc(II) chloride; In tetrachloromethane;

DOI:10.1021/jm00114a006

Reference yield:

3-Chlor-3-phenyl-propyl-ethylether (24491-59-6) → 4-Ethoxy-2-hydroxy-2-phenyl-butyric acid (137040-01-8)

Guidance literature:

Multi-step reaction with 4 steps

1: 20percent aq. KOH

2: chromic acid

3: ZnI₂ / CH₂Cl₂ / 24 h / Ambient temperature

4: 10 N HCl, HOAc / 72 h / Ambient temperature

With hydrogenchloride; potassium hydroxide; chromic acid; acetic acid; zinc(II) iodide; In dichloromethane;

DOI:10.1021/jm00114a006

Reference yield:

3-Chlor-3-phenyl-propyl-ethylether (24491-59-6) → 4-Ethoxy-2-hydroxy-2-phenyl-butyric acid ethyl ester (137040-08-5)

Guidance literature:

Multi-step reaction with 5 steps

1: 20percent aq. KOH

2: chromic acid

3: ZnI₂ / CH₂Cl₂ / 24 h / Ambient temperature

4: 10 N HCl, HOAc / 72 h / Ambient temperature

5: 83 percent / (CF₃SO₂)2O / 8 h / Heating

With hydrogenchloride; potassium hydroxide; trifluoromethylsulfonic anhydride; chromic acid; acetic acid; zinc(II) iodide; In dichloromethane;

DOI:10.1021/jm00114a006

upstream raw materials:

styrene

ethyl chloromethyl ether

Downstream raw materials:

3-ethoxy-1-phenyl-1-propanol

3-ethoxy-1-phenyl-1-propanone

4-Ethoxy-2-hydroxy-2-phenyl-butyric acid

4-Ethoxy-2-hydroxy-2-phenyl-butyramide