3-cyclopropylazetidin-3-ol hydrochloride

Base Information

• Chemical Name: 3-cyclopropylazetidin-3-ol hydrochloride
• CAS No.: 848192-93-8
• Molecular Formula: C6H11 N O . Cl H
• Molecular Weight: 149.61900
• Hs Code.: 2933990090
• Mol file: 848192-93-8.mol

Synonyms:3-Azetidinol,3-cyclopropyl-, hydrochloride (9CI); 3-Cyclopropylazetidin-3-ol hydrochloride

Chemical Property of 3-cyclopropylazetidin-3-ol hydrochloride

Chemical Property:

• PSA: 32.26000
• LogP: 0.86150
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

3-cyclopropylazetidin-3-olhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-cyclopropylazetidin-3-ol hydrochloride

There total 3 articles about 3-cyclopropylazetidin-3-ol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-benzhydryl-3-cyclopropyl-azetidin-3-ol (848192-90-5) → 3-cyclopropylazetidine-3-ol hydrochloride (848192-93-8)

Guidance literature:

With hydrogen; palladium dihydroxide; palladium on carbon; In methanol; water; under 2585.81 Torr;

Reference yield:

benzyl 3-cyclopropyl-3-hydroxyazetidine-1-carboxylate → 3-cyclopropylazetidine-3-ol hydrochloride (848192-93-8)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 5h; under 760.051 Torr;

Reference yield:

→ 3-cyclopropylazetidine-3-ol hydrochloride (848192-93-8)

Guidance literature:

upstream raw materials:

1-benzhydryl-3-cyclopropyl-azetidin-3-ol

Refernces

• 1、 -. "PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA". Page/Page column 78. . Retrieved 2017/01/26.
• 2、 -. "Cyclopropyl Fused Indolobenzazepine HCV NS5B Inhibitors". Page/Page column 25. . Retrieved 2008/06/13.