3-ETHYL-3-AZETIDINOL HYDROCHLORIDE

Base Information

• Chemical Name: 3-ETHYL-3-AZETIDINOL HYDROCHLORIDE
• CAS No.: 935668-00-1
• Molecular Formula: C5H11 N O . Cl H
• Molecular Weight: 137.60800
• Hs Code.: 2933990090
• Mol file: 935668-00-1.mol

Synonyms:3-Ethylazetidin-3-olhydrochloride

Chemical Property of 3-ETHYL-3-AZETIDINOL HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 0.027mmHg at 25°C
• Boiling Point: 218.3oC at 760 mmHg
• Flash Point: 85.8oC
• PSA: 32.26000
• LogP: 0.86150
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

3-Ethylazetidin-3-olhydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-ETHYL-3-AZETIDINOL HYDROCHLORIDE

There total 2 articles about 3-ETHYL-3-AZETIDINOL HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(diphenylmethyl)-3-ethyl-3-azetidinol (147293-65-0) → 3-Ethyl-3-azetidinol hydrochloride (935668-00-1)

Guidance literature:

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; In methanol; under 760.051 Torr;

DOI:10.1021/acs.jmedchem.7b00621

Reference yield:

→ 3-Ethyl-3-azetidinol hydrochloride (935668-00-1)

Guidance literature:

Reference yield:

3-Ethyl-3-azetidinol hydrochloride (935668-00-1) + 4,6-dichloro-1-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidine → 1-{6-chloro-1-[3-(methanesulfonyl)phenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-yl}-3-ethylazetidin-3-ol

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In 2-methyltetrahydrofuran; at 20 ℃; for 19.5h;

upstream raw materials:

1-(diphenylmethyl)-3-ethyl-3-azetidinol

Refernces

• 1、 -. "TAXANE COMPOUND WITH AZETIDINE RING STRUCTURE". Page/Page column 15. . Retrieved 2008/12/06.