[7,7-2H2]-1-bromoundecane

Base Information

• Chemical Name: [7,7-2H2]-1-bromoundecane
• CAS No.: 386223-65-0
• Molecular Formula: C₁₁H₂₃Br
• Molecular Weight: 237.192
• Mol file: 386223-65-0.mol

Synonyms:

Chemical Property of [7,7-2H2]-1-bromoundecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [7,7-2H2]-1-bromoundecane

There total 10 articles about [7,7-2H2]-1-bromoundecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

[7,7-2H2]-1-undecanol (386223-63-8) → [7,7-2H2]-1-bromoundecane (386223-65-0)

Guidance literature:

With N-Bromosuccinimide; In N,N-dimethyl-formamide; at 50 ℃; for 0.25h;

DOI:10.1021/jo010560w

Reference yield:

2-n-butyl-1,3-dithiane (21792-53-0) → [7,7-2H2]-1-bromoundecane (386223-65-0)

Guidance literature:

Multi-step reaction with 7 steps

1: 81 percent / n-BuLi / tetrahydrofuran / 1 h / -78 °C

2: 85 percent / N-bromosuccinimide / acetone; H₂O / 0.08 h / -20 °C

3: 92 percent / NaBD₄ / methanol / 1 h / 20 °C

4: 73 percent / trimethylamine hydrochloride; triethylamine / CH₂Cl₂ / 1.5 h / 0 °C

5: LiAlD₄ / diethyl ether / 3 h / 20 °C

6: 0.286 g / HCl / methanol / 16 h / 20 °C

7: 74 percent / N-bromosuccinimide / dimethylformamide / 0.25 h / 50 °C

With hydrogenchloride; N-Bromosuccinimide; n-butyllithium; lithium aluminium deuteride; sodium borodeuteride; trimethylamine hydrochloride; triethylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; acetone;

DOI:10.1021/jo010560w

Reference yield:

pentanal (110-62-3) → [7,7-2H2]-1-bromoundecane (386223-65-0)

Guidance literature:

Multi-step reaction with 8 steps

1: 93 percent / BF₃*OEt₂; acetic acid / CHCl₃ / 16 h / Heating

2: 81 percent / n-BuLi / tetrahydrofuran / 1 h / -78 °C

3: 85 percent / N-bromosuccinimide / acetone; H₂O / 0.08 h / -20 °C

4: 92 percent / NaBD₄ / methanol / 1 h / 20 °C

5: 73 percent / trimethylamine hydrochloride; triethylamine / CH₂Cl₂ / 1.5 h / 0 °C

6: LiAlD₄ / diethyl ether / 3 h / 20 °C

7: 0.286 g / HCl / methanol / 16 h / 20 °C

8: 74 percent / N-bromosuccinimide / dimethylformamide / 0.25 h / 50 °C

With hydrogenchloride; N-Bromosuccinimide; n-butyllithium; lithium aluminium deuteride; sodium borodeuteride; boron trifluoride diethyl etherate; trimethylamine hydrochloride; acetic acid; triethylamine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane; chloroform; water; N,N-dimethyl-formamide; acetone;

DOI:10.1021/jo010560w

upstream raw materials:

[7,7-2H₂]-1-undecanol

2-n-butyl-1,3-dithiane

pentanal

1-bromo-6-hexanol