tert-Butyl (4-fluoropyrrolidin-3-yl)carbamate

Base Information

• Chemical Name: tert-Butyl (4-fluoropyrrolidin-3-yl)carbamate
• CAS No.: 351369-12-5
• Molecular Formula: C₉H₁₇FN₂O₂
• Molecular Weight: 204.245
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60599248
• Mol file: 351369-12-5.mol

Synonyms:351369-12-5;tert-Butyl (4-fluoropyrrolidin-3-yl)carbamate;TERT-BUTYL N-(4-FLUOROPYRROLIDIN-3-YL)CARBAMATE;TERT-BUTYL (4-FLUORO-3-PYRROLIDINYL)CARBAMATE;169750-42-9;TERT-BUTYL 4-FLUOROPYRROLIDIN-3-YLCARBAMATE;Carbamic acid, (4-fluoro-3-pyrrolidinyl)-, 1,1-dimethylethyl ester (9CI);(4-Fluoro-pyrrolidin-3-yl)-carbamic acid tert-butyl ester;(3-Boc-amino)-4-fluoropyrrolidine;Carbamic acid, N-[(3R,4S)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester;MFCD24368650;MFCD24368651;(3S,4S)-3-(Boc-amino)-4-fluoropyrrolidine;tert-butyl N-[cis-4-fluoropyrrolidin-3-yl]carbamate;tert-butyl N-[trans-4-fluoropyrrolidin-3-yl]carbamate;SCHEMBL4519280;CIS-(4-FLUORO-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER;TRANS-(4-FLUORO-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER;DTXSID60599248;AMY23903;MFCD10566553;AKOS024076472;AB56263;SB12380;SB12381;SB12384;SB12385;SB13121;SB13123;AS-50705;SY099072;SY128728;SY130876;DB-352751;(3S,4R)-N-Boc-4-fluoropyrrolidin-3-amine;CS-0048067;tert-Butyl(4-fluoropyrrolidin-3-yl)carbamate;(3R,4S)-(3-Boc-amino)-4-fluoropyrrolidine;P10920;A874751;(3R,4R)-3-Amino-4-fluoropyrrolidine, 3-BOC protected;(4-Fluoropyrrolidin-3-yl)carbamic acid tert-butyl ester;Carbamic acid, N-[(3R,4R)-4-fluoro-3-pyrrolidinyl]-, 1,1-dimethylethyl ester

Chemical Property of tert-Butyl (4-fluoropyrrolidin-3-yl)carbamate

Chemical Property:

• Vapor Pressure: 0.00153mmHg at 25°C
• Refractive Index: 1.463
• Boiling Point: 295.3 °C at 760 mmHg
• Flash Point: 132.4 °C
• PSA: 50.36000
• Density: 1.1 g/cm³
• LogP: 1.54070
• Storage Temp.: 2-8°C(protect from light)
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 204.12740595
• Heavy Atom Count: 14
• Complexity: 215

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(4-Fluoro-3-pyrrolidinyl)carbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)OC(=O)NC1CNCC1F

Technology Process of tert-Butyl (4-fluoropyrrolidin-3-yl)carbamate

There total 1 articles about tert-Butyl (4-fluoropyrrolidin-3-yl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ cis-3-(BOC-amino)-4-fluoropyrrolidine (351369-12-5,169750-42-9,213388-71-7,213388-72-8,1033718-89-6,1033718-91-0)

Guidance literature: