1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan

Base Information

• Chemical Name: 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan
• CAS No.: 102030-27-3
• Molecular Formula: C₂₁H₂₄
• Molecular Weight: 276.422
• Mol file: 102030-27-3.mol

Synonyms:

Chemical Property of 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan

There total 3 articles about 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,2-diphenyl-cyclopropanecarboxylic acid (7150-12-1) → 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan (102030-27-3)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) SOCl₂, (ii) NaN₃, (iii) (heating in benzene), (iv) NH₃

2: aq. NaNO₂, AcOH, Ac₂O

3: LiOEt

With acetic anhydride; lithium ethoxide; acetic acid; sodium nitrite;

DOI:10.1021/ja00901a018

Reference yield:

2-Carbamoylamino-1,1-diphenyl-cyclopropan (92965-97-4) → 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan (102030-27-3)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaNO₂, AcOH, Ac₂O

2: LiOEt

With acetic anhydride; lithium ethoxide; acetic acid; sodium nitrite;

DOI:10.1021/ja00901a018

Reference yield:

2,3-Dimethyl-2-butene (563-79-1) + N-(2,2-diphenylcyclopropyl)-N-nitrosourea (5909-90-0) → 1,1,2,2-Tetramethyl-4,4-diphenyl-spiropentan (102030-27-3)

Guidance literature:

With lithium ethoxide;

DOI:10.1021/ja00901a018

upstream raw materials:

2,3-Dimethyl-2-butene

N-(2,2-diphenylcyclopropyl)-N-nitrosourea

2,2-diphenyl-cyclopropanecarboxylic acid

2-Carbamoylamino-1,1-diphenyl-cyclopropan