(S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

Base Information

Chemical Name:(S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine
CAS No.:1150639-56-7
Molecular Formula:C₃₂H₃₆N₂O₁₀S₂
Molecular Weight:672.777
Hs Code.:

(S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

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Chemical Property of (S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

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Technology Process of (S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

There total 1 articles about (S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1150639-53-4
(S)-1-{[1'-[4-(2-bromo-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

: 2386-52-9
silver methanesulfonate

: 1150639-56-7
(S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

Guidance literature:: In acetonitrile; Reflux; Inert atmosphere;
DOI:10.1039/b819024k

Reference yield:

: 1150639-56-7
(S)-1-{[1'-[4-(2-methanesulfonyloxy-ethoxy)-benzyl]-1',2'-dihydro-2'-oxospiro(1,3-dioxane-2,3'-[3H]indol)-5'-yl]sulfonyl}-2-(phenoxymethyl)-pyrrolidine

: 1150639-61-4
C₃₁H₃₃⁽¹⁸⁾FN₂O₇S

Guidance literature:: With ¹⁸F-fluoride; K₂₂₂; potassium carbonate; In dimethyl sulfoxide; acetonitrile; Microwave irradiation; Inert atmosphere;
DOI:10.1039/b819024k