3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline

Base Information

Chemical Name:3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline
CAS No.:154057-56-4
Molecular Formula:C19H15BrFN
Molecular Weight:356.237
Hs Code.:2933499090
Mol file:154057-56-4.mol

Synonyms:Quinoline,3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)-;

Suppliers and Price of 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline
2.5g
$ 155.00

TRC
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline
1g
$ 110.00

Matrix Scientific
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline 95+%
1g
$ 94.00

Matrix Scientific
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline 95+%
5g
$ 279.00

Crysdot
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline 95+%
5g
$ 295.00

Chemenu
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline 95%
5g
$ 757.00

Chemenu
3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline 95%
1g
$ 252.00

AvaChem
3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline
1g
$ 95.00

AvaChem
3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline
1kg
$ 5800.00

AvaChem
3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline
10g
$ 350.00

Total 113 raw suppliers

Chemical Property of 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline

Chemical Property:

Boiling Point:467.62 °C at 760 mmHg
PKA:4.32±0.50(Predicted)
Flash Point:236.608 °C
PSA：12.89000
Density:1.461 g/cm³
LogP:5.81320
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly, Heated)

Purity/Quality:

≥98.0% ^*data from raw suppliers

3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 3-(Bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline is used to prepare artificial HMG-CoA reductase inhibitors. It is also used to synthesize pitavastatin calcium via stereoselective Wittig olefination reaction.

Technology Process of 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline

There total 4 articles about 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 121660-11-5
2-cyclopropyl-4-(4-fluorophenyl)-3-(hydroxymethyl)quinoline

: 154057-56-4
3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)-quinoline

Guidance literature:: With phosphorus tribromide; In dichloromethane; toluene; for 3h; Ambient temperature;
DOI:10.1246/bcsj.68.364

Reference yield: 86.0%

: 121660-37-5
2-cyclopropyl-4-(4-fluorophenyl)-3-formylquinoline

: 154057-56-4
3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)-quinoline

Guidance literature:: With Dichloromethylsilane; iron(III) chloride; phosphorus tribromide; In acetonitrile; at 75 - 85 ℃; Temperature; Inert atmosphere;