2,4-Dibromoquinoline

Base Information

• Chemical Name: 2,4-Dibromoquinoline
• CAS No.: 20151-40-0
• Molecular Formula: C9H5Br2N
• Molecular Weight: 286.953
• Hs Code.: 2933499090
• European Community (EC) Number: 623-661-2
• DSSTox Substance ID: DTXSID00356453
• Nikkaji Number: J82.933A
• Wikidata: Q72465020
• Mol file: 20151-40-0.mol

Synonyms:2,4-dibromoquinoline;20151-40-0;2,4-Dibromo-quinoline;Quinoline, 2,4-dibromo-;2,4-Dibromoquinoline, 97%;SCHEMBL1257332;DTXSID00356453;CYRONKIISXPXER-UHFFFAOYSA-N;MFCD00837761;ZB0108;AKOS015994866;SB71871;DS-15204;A4395;CS-0103202;FT-0710274;C73820;EN300-312530;AC-907/34106024;J-507105

Chemical Property of 2,4-Dibromoquinoline

Chemical Property:

• Vapor Pressure: 0.000132mmHg at 25°C
• Melting Point: 92-94 °C
• Refractive Index: 1.698
• Boiling Point: 344.3 °C at 760 mmHg
• PKA: -1.12±0.50(Predicted)
• Flash Point: 162 °C
• PSA: 12.89000
• Density: 1.923 g/cm³
• LogP: 3.75980
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 286.87682
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

97% ^*data from raw suppliers

2,4-Dibromoquinoline 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25-37/38-41
• Safety Statements: 26-39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C(=CC(=N2)Br)Br

Technology Process of 2,4-Dibromoquinoline

There total 12 articles about 2,4-Dibromoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-Hydroxy-2-quinolone (70254-43-2,70254-44-3,86-95-3) → 2,4-dibromoquinoline (20151-40-0)

Guidance literature:

With phosphorus(V) oxybromide;

Reference yield: 86.0%

2,4-dihydroxyquinoline (70254-44-3) → 2,4-dibromoquinoline (20151-40-0)

Guidance literature:

With phosphorus(V) oxybromide; for 0.5h; Heating;

Reference yield: 76.0%

malonic acid (141-82-2) + aniline (62-53-3) → 2,4-dibromoquinoline (20151-40-0)

Guidance literature:

With phosphorus(V) oxybromide; at 130 - 140 ℃; for 3h;

upstream raw materials:

2,4-dihydroxyquinoline

2-bromo-4-nitroquinoline

4-nitroquinoline-N-oxide

4-Hydroxy-2-quinolone

Downstream raw materials:

4-(2'-bromo-4'-quinolyl)-2-phenyl-3-butyn-2-ol

1-(2'-bromo-4'-quinolyl)-2-phenylacetylene

2-bromo‐4‐chloroquinoline

4-bromo-2-hydroxyquinoline