Technology Process of 3''-benzyl-2'-isobutyl-3-isopropyl[1,1':4',1'']terphenyl
There total 10 articles about 3''-benzyl-2'-isobutyl-3-isopropyl[1,1':4',1'']terphenyl which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate;
In
1,2-dimethoxyethane;
at 80 ℃;
for 24h;
Inert atmosphere;
DOI:10.1002/chem.201203005
- Guidance literature:
-
Multi-step reaction with 5 steps
1: hydrogen; palladium 10% on activated carbon / methanol / 3 h / 20 °C
2: Iodine monochloride / acetic acid / 48 h / 20 °C
3: pyridine / 24 h / 0 - 20 °C / Inert atmosphere; Schlenk technique
4: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; cesium fluoride / 1,2-dimethoxyethane / 2 h / 80 °C / Inert atmosphere
5: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate / 1,2-dimethoxyethane / 24 h / 80 °C / Inert atmosphere
With
pyridine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; palladium 10% on activated carbon; hydrogen; Iodine monochloride; caesium carbonate; cesium fluoride;
In
methanol; 1,2-dimethoxyethane; acetic acid;
4: |Suzuki Coupling / 5: |Suzuki Coupling;
DOI:10.1002/chem.201203005
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: n-butyllithium / tetrahydrofuran / 4 h / -78 °C / Inert atmosphere; Schlenk technique
1.2: 1.5 h / -78 °C / Inert atmosphere; Schlenk technique
2.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; cesium fluoride / 1,2-dimethoxyethane / 2 h / 80 °C / Inert atmosphere
3.1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate / 1,2-dimethoxyethane / 24 h / 80 °C / Inert atmosphere
With
n-butyllithium; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; caesium carbonate; cesium fluoride;
In
tetrahydrofuran; 1,2-dimethoxyethane;
2.1: |Suzuki Coupling / 3.1: |Suzuki Coupling;
DOI:10.1002/chem.201203005
