1-(propylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol

Base Information

Chemical Name:1-(propylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol
CAS No.:102151-07-5
Molecular Formula:C₁₉H₂₃N₃O₂S
Molecular Weight:357.477
Hs Code.:
ChEMBL ID:CHEMBL274830
DSSTox Substance ID:DTXSID00875154
Nikkaji Number:J1.550.917A

Synonyms:CHEMBL274830;102151-07-5;DTXSID00875154;BDBM50405406;2-PROPANOL, 1-(PROPYLAMINO)-3-[4-[5-(2-THIENYL)-

Suppliers and Price of 1-(propylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(propylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:357.15109816
Heavy Atom Count:25
Complexity:380

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCNCC(COC1=CC=C(C=C1)C2=NC=C(N2)C3=CC=CS3)O

Technology Process of 1-(propylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol

There total 3 articles about 1-(propylamino)-3-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)phenoxy]propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-Phenyl-3-propyl-5-[4-(5-thiophen-2-yl-1H-imidazol-2-yl)-phenoxymethyl]-oxazolidine

: 102151-07-5
2-<4-<3-(n-propylamino)-2-hydroxypropoxy>phenyl>-4-(2-thienyl)imidazole

Guidance literature:: With water; acetic acid; for 18h; Yield given; Ambient temperature;
DOI:10.1021/jm00156a028

Reference yield:

: 102151-78-0
Toluene-4-sulfonic acid 2-phenyl-3-propyl-oxazolidin-5-ylmethyl ester

: 102151-07-5
2-<4-<3-(n-propylamino)-2-hydroxypropoxy>phenyl>-4-(2-thienyl)imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 70 deg C, 15 min, 2.) DMF, 120 deg C, 18 h

2: H₂O, AcOH / 18 h / Ambient temperature

With water; sodium hydride; acetic acid;
DOI:10.1021/jm00156a028

Reference yield:

: 70552-22-6
2-(p-hydroxyphenyl)-4-(2-thienyl)imidazole

: 102151-07-5
2-<4-<3-(n-propylamino)-2-hydroxypropoxy>phenyl>-4-(2-thienyl)imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, 70 deg C, 15 min, 2.) DMF, 120 deg C, 18 h

2: H₂O, AcOH / 18 h / Ambient temperature

With water; sodium hydride; acetic acid;
DOI:10.1021/jm00156a028