3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol

Base Information

• Chemical Name: 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol
• CAS No.: 43169-59-1
• Molecular Formula: C₁₆H₂₃NO₃
• Molecular Weight: 277.364
• Mol file: 43169-59-1.mol

Synonyms:

Chemical Property of 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol

There total 4 articles about 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3(a)-Amino-2(e)-<3,4-dibenzyloxy-phenyl>-trans-2(a)-decalol; (+/-)-3c-Amino-2c-<3,4-dibenzyloxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol (31796-44-8) → 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol (43169-59-1,43169-60-4,43169-61-5,43169-62-6,52670-41-4,52691-80-2,52691-81-3,52691-82-4)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00287a001

Reference yield:

2(e)-<3,4-Dibenzyloxy-phenyl>-trans-decalin-2,3-oxid, (+/-)-2c-<3,4-Dibenzyloxy-phenyl>-2t,3t-epoxy-(4ar,8at)-decahydro-naphthalin → 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol (43169-59-1,43169-60-4,43169-61-5,43169-62-6,52670-41-4,52691-80-2,52691-81-3,52691-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: liq. NH₃ / 155 °C

2: H₂ / Pd-C / methanol

With ammonia; hydrogen; palladium on activated charcoal; In methanol;

DOI:10.1021/jm00287a001

Reference yield:

2(e)-<3,4-Dibenzyloxy-phenyl>-2(a)-hydroxy-trans-3-decalon-oxim, (+/-)-2c-<3,4-Dibenzyloxy-phenyl>-3-hydroxyimino-(4ar,8at)-decahydro-<2t>-naphthol → 3(a)-Amino-2(e)-<3,4-dihydroxy-phenyl>-trans-2(a)decalol; (+/-)-3c-Amino-2c-<3,4-dihydroxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol (43169-59-1,43169-60-4,43169-61-5,43169-62-6,52670-41-4,52691-80-2,52691-81-3,52691-82-4)

Guidance literature:

Multi-step reaction with 2 steps

1: Na2(OCH₂CH₂OMe)2> / benzene; tetrahydrofuran

2: H₂ / Pd-C / methanol

With hydrogen; sodium bis(2-methoxyethoxy)aluminium dihydride; palladium on activated charcoal; In tetrahydrofuran; methanol; benzene;

DOI:10.1021/jm00287a001

upstream raw materials:

3(a)-Amino-2(e)-<3,4-dibenzyloxy-phenyl>-trans-2(a)-decalol; (+/-)-3c-Amino-2c-<3,4-dibenzyloxy-phenyl>-(4ar,8at)-decahydro-<2t>-naphthol