N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide

Base Information

• Chemical Name: N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide
• CAS No.: 303127-33-5
• Molecular Formula: C₁₃H₁₁ClN₂O₂S
• Molecular Weight: 294.762
• DSSTox Substance ID: DTXSID701323020
• ChEMBL ID: CHEMBL1389324
• Mol file: 303127-33-5.mol

Synonyms:N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide;303127-33-5;N-(5-acetyl-4-methylthiazol-2-yl)-4-chlorobenzamide;MFCD01930865;MLS000764868;CHEMBL1389324;DTXSID701323020;HMS2774N18;STK136783;AKOS000538520;LS-07520;SMR000290473;UPCMLD0ENAT0501-2079:001;AB00661561-02;AF-886/31411036;Z29870255;F0060-0034

Chemical Property of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide

Chemical Property:

• XLogP3: 3.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 294.0229765
• Heavy Atom Count: 19
• Complexity: 359

Purity/Quality:

N-(5-Acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C(SC(=N1)NC(=O)C2=CC=C(C=C2)Cl)C(=O)C

Technology Process of N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide

There total 1 articles about N-(5-acetyl-4-methyl-1,3-thiazol-2-yl)-4-chlorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4-chloro-benzoyl)-thiourea (38334-94-0) + 3-chloropentane-2,4-dione (1694-29-7) → C13H11ClN2O2S (303127-33-5)

Guidance literature:

In ethanol; Heating;

DOI:10.1016/j.bmcl.2008.03.037

Reference yield:

C13H11ClN2O2S (303127-33-5) → C13H10BrClN2O2S

Guidance literature:

With hydrogen bromide; pyridinium hydrobromide perbromide; In acetic acid; at 20 ℃;

DOI:10.1016/j.bmcl.2008.03.037

upstream raw materials:

(4-chloro-benzoyl)-thiourea

3-chloropentane-2,4-dione