3-[4-(Heptyloxy)phenyl]-2-propenoic acid

Base Information

• Chemical Name: 3-[4-(Heptyloxy)phenyl]-2-propenoic acid
• CAS No.: 110683-38-0
• Molecular Formula: C16H22 O3
• Molecular Weight: 262.34400
• Mol file: 110683-38-0.mol

Synonyms:4-(Heptyloxy)cinnamicacid

Chemical Property of 3-[4-(Heptyloxy)phenyl]-2-propenoic acid

Chemical Property:

• Vapor Pressure: 1.33E-07mmHg at 25°C
• Boiling Point: 414.2±20.0 °C(Predicted)
• PKA: 4.61±0.10(Predicted)
• Flash Point: 147.9°C
• PSA: 46.53000
• Density: 1.057
• LogP: 4.13360

Purity/Quality:

99% ^*data from raw suppliers

4-(HEPTYLOXY)CINNAMIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-[4-(Heptyloxy)phenyl]-2-propenoic acid

There total 7 articles about 3-[4-(Heptyloxy)phenyl]-2-propenoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

malonic acid (141-82-2) + 4-(n-heptyloxy)benzaldehyde (27893-41-0) → (E)-3-(4-Heptyloxy-phenyl)-acrylic acid (110683-38-0)

Guidance literature:

Reference yield:

1-Bromoheptane (629-04-9) → (E)-3-(4-Heptyloxy-phenyl)-acrylic acid (110683-38-0)

Guidance literature:

Multi-step reaction with 2 steps

1: K₂CO₃ / acetone

2: pyridine

With pyridine; potassium carbonate; In acetone;

DOI:10.1080/10587250307066

Reference yield:

4-hydroxy-benzaldehyde (123-08-0,65581-83-1) → (E)-3-(4-Heptyloxy-phenyl)-acrylic acid (110683-38-0)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone

2: piperidine / Reflux

With piperidine; potassium carbonate; In acetone;

DOI:10.1080/10426507.2012.673943

upstream raw materials:

malonic acid

4-(n-heptyloxy)benzaldehyde

1-Bromoheptane

4-hydroxy-benzaldehyde

Downstream raw materials:

(E)-3-(4-Heptyloxy-phenyl)-acryloyl chloride

(E)-3-(4-Heptyloxy-phenyl)-acrylic acid 4-formyl-phenyl ester