(-)-(R,R)-1,2-cyclohexanedisulfonic acid

Base Information

• Chemical Name: (-)-(R,R)-1,2-cyclohexanedisulfonic acid
• CAS No.: 94000-10-9
• Molecular Formula: C₆H₁₂O₆S₂
• Molecular Weight: 244.29
• Mol file: 94000-10-9.mol

Synonyms:

Chemical Property of (-)-(R,R)-1,2-cyclohexanedisulfonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (-)-(R,R)-1,2-cyclohexanedisulfonic acid

There total 9 articles about (-)-(R,R)-1,2-cyclohexanedisulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(S,S)-1,2-cyclohexanediammonium (R,R)-1,2-cyclohexanedisulfonate → (-)-(R,R)-1,2-cyclohexanedisulfonic acid (46249-71-2,94000-10-9)

Guidance literature:

With Amberlyst 15; In water;

DOI:10.1002/ejic.201402925

Reference yield:

cyclohexane-1,2-epoxide (286-20-4) → (-)-(R,R)-1,2-cyclohexanedisulfonic acid (46249-71-2,94000-10-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium hydroxide / methanol / 4 h / 0 - 23 °C

2.1: dihydrogen peroxide; acetic acid / water / 20 h / 23 °C

3.1: Amberlyst 15 / water

3.2: Resolution of racemate

4.1: Amberlyst 15 / water

With dihydrogen peroxide; acetic acid; potassium hydroxide; In methanol; water;

DOI:10.1002/ejic.201402925

Reference yield:

(±)-barium trans-1,2-cyclohexanedisulfonate → (-)-(R,R)-1,2-cyclohexanedisulfonic acid (46249-71-2,94000-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: Amberlyst 15 / water

1.2: Resolution of racemate

2.1: Amberlyst 15 / water

With Amberlyst 15; In water;

DOI:10.1002/ejic.201402925

upstream raw materials:

trans-3a,4,5,6,7,7a-Hexahydro-2H-1,3-benzodithiole-2-thione

cyclohexane-1,2-epoxide

cyclohexene