Welcome to LookChem.com Sign In|Join Free
  • or

Encyclopedia

Technology Process of 4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide

4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide

Base Information
  • Chemical Name:4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide
  • CAS No.:870223-96-4
  • Molecular Formula:C25H20F3N5O2
  • Molecular Weight:479.45
  • Hs Code.:
  • ChEMBL ID:CHEMBL218632
  • DSSTox Substance ID:DTXSID20582974
  • Pharos Ligand ID:NC8BZ2M9GSS6
  • Wikidata:Q72492731
  • Mol file:870223-96-4.mol
4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide

Synonyms:AMG-Tie2-1;870223-96-4;4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide;AMG-Tie 2-1;4-METHYL-3-[[3-[2-(METHYLAMINO)-4-PYRIMIDINYL]-2-PYRIDINYL]OXY]-N-[3-(TRIFLUOROMETHYL)PHENYL]BENZAMIDE;4-methyl-3-(3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yloxy)-N-(3-(trifluoromethyl)phenyl)benzamide;4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-N-[3-(trifluoromethyl)phenyl]benzamide;4-methyl-3-[[3-[2-(methylamino)-4-pyrimidinyl]-2-pyridinyl]oxy]-N-[3-(trifluoromethyl)phenyl]-benzamide;ZVIWALRWYYSHSU-UHFFFAOYSA-N;4-methyl-3-((3-(2-(methylamino)-4-pyrimidinyl)-2-pyridinyl)oxy)-n-(3-(trifluoromethyl)phenyl)benzamide;pyridinyl pyrimidine 15;pyridylpyrimidine ether 4;CHEMBL218632;SCHEMBL1264498;BDBM14948;DTXSID20582974;BCPP000406;HMS3244C13;HMS3244C14;HMS3244D13;BCP01978;AKOS027420933;BCP9000290;NCGC00263199-01;NCGC00263199-02;NCGC00263199-03;AS-16183;HY-13023;CS-0003158;A19396;J-515730;4-methyl-3-[3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl]oxy-N-[3-(trifluoromethyl)phenyl]benzamide

Suppliers and Price of 4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Matrix Scientific
  • 4-Methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide 97%
  • 10g
  • $ 8100.00
  • Matrix Scientific
  • 4-Methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide 97%
  • 5g
  • $ 4860.00
  • DC Chemicals
  • AMG-Tie2-1 >98%
  • 1 g
  • $ 2900.00
  • Cayman Chemical
  • AMG-Tie2-1
  • 25mg
  • $ 663.00
  • Cayman Chemical
  • AMG-Tie2-1
  • 10mg
  • $ 341.00
  • Cayman Chemical
  • AMG-Tie2-1
  • 5mg
  • $ 180.00
  • Cayman Chemical
  • AMG-Tie2-1
  • 1mg
  • $ 39.00
  • American Custom Chemicals Corporation
  • AMG-TIE2-1 95.00%
  • 1MG
  • $ 345.45
  • American Custom Chemicals Corporation
  • AMG-TIE2-1 95.00%
  • 5MG
  • $ 501.00
  • Adipogen Life Sciences
  • AMG-Tie2-1 ≥95%
  • 5 mg
  • $ 421.00
Total 14 raw suppliers
Chemical Property of 4-methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide
Chemical Property:
  • PSA：95.75000 
  • Density:1.357 g/cm3 
  • LogP:5.75800 
  • XLogP3:5.1
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:9
  • Rotatable Bond Count:6
  • Exact Mass:479.15690938
  • Heavy Atom Count:35
  • Complexity:697
Purity/Quality:

97% *data from raw suppliers

4-Methyl-3-((3-(2-(methylamino)pyrimidin-4-yl)pyridin-2-yl)oxy)-N-(3-(trifluoromethyl)phenyl)benzamide 97% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC1=C(C=C(C=C1)C(=O)NC2=CC=CC(=C2)C(F)(F)F)OC3=C(C=CC=N3)C4=NC(=NC=C4)NC
  • Description AMG-Tie2-1 is an inhibitor of tunica interna endothelial cell kinase 2 (Tie2) and VEGF receptor 2 (VEGFR2) with IC50 values of 1 and 3 nM, respectively, in a homogenous time-resolved fluorescence (HTRF) assay. It inhibits angiopoietin 1-induced Tie2 autophosphorylation in EA.hy926 human endothelial cells (IC50 = 10 nM).
  • Uses AMG-Tie 2-1 is a pyridinyltriazine Tie-2 kinase inhibitor. A useful research chemical for cancer metabolism research studies.
Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 870223-96-4

Total 8 Pictures about this product