Saredutant

Base Information

Chemical Name:Saredutant
CAS No.:159125-41-4
Molecular Formula:C₃₁H₃₅Cl₂N₃O₂
Molecular Weight:552.544
Hs Code.:
Mol file:159125-41-4.mol

Synonyms:SR 48212A;Saredutant;N-[4-[4-(Acetylamino)-4-phenyl-1-piperidinyl]-2-(3,4-dichlorophenyl)butyl]-N-methylbenzamide;

Suppliers and Price of Saredutant

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Saredutant

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Refractive Index:1.628
Boiling Point:734.669 °C at 760 mmHg
PKA:15.88±0.20(Predicted)
Flash Point:398.114 °C
PSA：56.14000
Density:1.26 g/cm³
LogP:7.14490

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Saredutant

There total 8 articles about Saredutant which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-17-8,26099-09-2
(2E)-but-2-enedioic acid

: 146396-04-5
N-(4-phenylpiperidin-4-yl)acetamide

: 142001-63-6,159125-41-4
SR 48212A

Guidance literature:: With hydrogenchloride; sodium hydroxide; In dichloromethane; water; potassium carbonate; acetone; acetonitrile;

Reference yield:

: 3218-49-3
3,4-dichloro-benzeneacetonitrile

: 142001-63-6,159125-41-4
SR 48212A

Guidance literature:: Multi-step reaction with 6 steps

1: NaH / dimethylformamide

2: H₂ / Raney nickel / acidic solution

3: BH₃ / tetrahydrofuran

4: NEt₃ / CH₂Cl₂ / 20 °C

5: NEt₃ / CH₂Cl₂

6: K₂CO₃ / dimethylformamide

With borane; hydrogen; sodium hydride; potassium carbonate; triethylamine; nickel; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00343-3

Reference yield:

: 135936-16-2
α-[2-(Tetrahydropyran-2-yloxy)ethyl]-3,4-dichlorophenyl-acetonitrile

: 142001-63-6,159125-41-4
SR 48212A

Guidance literature:: Multi-step reaction with 5 steps

1: H₂ / Raney nickel / acidic solution

2: BH₃ / tetrahydrofuran

3: NEt₃ / CH₂Cl₂ / 20 °C

4: NEt₃ / CH₂Cl₂

5: K₂CO₃ / dimethylformamide

With borane; hydrogen; potassium carbonate; triethylamine; nickel; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0960-894X(03)00343-3