Technology Process of 1-(N6-benzoyladenin-9-yl)-2,3-O-dibenzoyl-3-vinyl-β-D-erythrofuranose
There total 4 articles about 1-(N6-benzoyladenin-9-yl)-2,3-O-dibenzoyl-3-vinyl-β-D-erythrofuranose which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
N-benzoyladenine;
With
ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane;
Inert atmosphere;
Reflux;
1,2,3-O-tribenzoyl-3-vinyl-D-erythrofuranose;
With
tin(IV) chloride;
In
acetonitrile;
at 20 ℃;
for 1.5h;
Inert atmosphere;
DOI:10.1021/jo200033p
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
2.1: trifluoroacetic acid / water / 0 - 20 °C
3.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane / Inert atmosphere; Reflux
4.2: 1.5 h / 20 °C / Inert atmosphere
With
dmap; ammonium sulfate; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; trifluoroacetic acid;
In
dichloromethane; water;
DOI:10.1021/jo200033p
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: trifluoroacetic acid / water / 0 - 20 °C
2.1: dmap; triethylamine / dichloromethane / 0 - 20 °C / Inert atmosphere
3.1: ammonium sulfate; 1,1,1,3,3,3-hexamethyl-disilazane / Inert atmosphere; Reflux
3.2: 1.5 h / 20 °C / Inert atmosphere
With
dmap; ammonium sulfate; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; trifluoroacetic acid;
In
dichloromethane; water;
DOI:10.1021/jo200033p
