Technology Process of 5-<4-(1-oxo-2-phenoxyethyl)benzyl>thiazolidine-2,4-dione
There total 10 articles about 5-<4-(1-oxo-2-phenoxyethyl)benzyl>thiazolidine-2,4-dione which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
chromic acid;
In
diethyl ether;
for 2h;
Ambient temperature;
DOI:10.1021/jm00088a022
- Guidance literature:
-
Multi-step reaction with 7 steps
1: sodium borohydride / propan-2-ol; CH2Cl2 / 1 h
2: 61 percent / imidazole / dimethylformamide / 36 h / Ambient temperature
3: 1.) BuLi / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, DMF, -78 deg C, 1 h
4: sodium acetate / 2 h / 140 °C
5: 3percent sodium amalgam / methanol / 20 h
6: 64 percent / 3.5percent perchloric acid / tetrahydrofuran / Ambient temperature
7: chromic acid / diethyl ether / 2 h / Ambient temperature
With
1H-imidazole; sodium tetrahydroborate; sodium amalgam; n-butyllithium; perchloric acid; sodium acetate; chromic acid;
In
tetrahydrofuran; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol;
DOI:10.1021/jm00088a022
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 61 percent / imidazole / dimethylformamide / 36 h / Ambient temperature
2: 1.) BuLi / 1.) THF, hexane, -78 deg C, 1 h, 2.) THF, hexane, DMF, -78 deg C, 1 h
3: sodium acetate / 2 h / 140 °C
4: 3percent sodium amalgam / methanol / 20 h
5: 64 percent / 3.5percent perchloric acid / tetrahydrofuran / Ambient temperature
6: chromic acid / diethyl ether / 2 h / Ambient temperature
With
1H-imidazole; sodium amalgam; n-butyllithium; perchloric acid; sodium acetate; chromic acid;
In
tetrahydrofuran; methanol; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jm00088a022
