7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione

Base Information

Chemical Name:7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
CAS No.:77350-99-3
Molecular Formula:C₁₆H₁₇N₅O₃
Molecular Weight:327.343
Hs Code.:
DSSTox Substance ID:DTXSID601322281
ChEMBL ID:CHEMBL1565780

Synonyms:77350-99-3;7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione;7-hydroxy-1-methyl-9-(p-tolyl)-6,7,8,9-tetrahydropyrimido[2,1-f]purine-2,4(1H,3H)-dione;Oprea1_586007;Oprea1_697945;MLS001207990;CHEMBL1565780;DTXSID601322281;HMS2817J16;STK633905;AKOS000576984;AKOS005567794;AKOS016874998;6-Hydroxy-1-methyl-8-p-tolyl-5,6,7,8-tetrahydro-1H-1,3,4b,8,9-pentaaza-fluorene-2,4-dione;SMR000513286;VU0488186-1;Z56762946;F0017-0818;4,7-dihydroxy-1-methyl-9-(4-methylphenyl)-6,7,8,9-tetrahydropyrimido[2,1-f]purin-2(1H)-one

Suppliers and Price of 7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:327.13313942
Heavy Atom Count:24
Complexity:536

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)N2CC(CN3C2=NC4=C3C(=O)NC(=O)N4C)O

Technology Process of 7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione

There total 2 articles about 7-hydroxy-1-methyl-9-(4-methylphenyl)-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 106-49-0,12221-03-3
p-toluidine

: 77350-94-8
8-chloro-7-(γ-chloro-β-hydroxypropyl)-3-methylxanthine

: 77350-99-3
6-Hydroxy-1-methyl-8-p-tolyl-5,6,7,8-tetrahydro-1H-1,3,4b,8,9-pentaaza-fluorene-2,4-dione

Guidance literature:: In N,N-dimethyl-formamide; for 5h; Heating;
DOI:10.1007/BF00571034

Reference yield:

: 77350-93-7
3-methyl-8-chloroxanthine

: 77350-99-3
6-Hydroxy-1-methyl-8-p-tolyl-5,6,7,8-tetrahydro-1H-1,3,4b,8,9-pentaaza-fluorene-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 51 percent / pyridine / propan-1-ol / 2 h / Heating

2: 58 percent / dimethylformamide / 5 h / Heating

With pyridine; In propan-1-ol; N,N-dimethyl-formamide;
DOI:10.1007/BF00571034