Squalene-2,3-diol

Base Information

Chemical Name:Squalene-2,3-diol
CAS No.:14031-37-9
Molecular Formula:C30H52 O2
Molecular Weight:444.742
Hs Code.:
Mol file:14031-37-9.mol

Synonyms:(?à)-Squalene-2,3-diol;2,3-Dihydroxysqualene; Squalene glycol; Squalene-2,3-glycol

Suppliers and Price of Squalene-2,3-diol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Squalene-2,3-glycol
10mg
$ 165.00

Medical Isotopes, Inc.
Squalene-2,3-glycol
50 mg
$ 900.00

Arctom
Squalene-2,3-diol ≥98%
5mg
$ 463.00

Total 19 raw suppliers

Chemical Property of Squalene-2,3-diol

Chemical Property:

Boiling Point:550.9±38.0 °C(Predicted)
PKA:14.66±0.29(Predicted)
PSA：40.46000
Density:0.914±0.06 g/cm3(Predicted)
LogP:8.77060
Storage Temp.:Refrigerator
Solubility.:Chloroform, Dichloromethane, Ethyl Acetate

Purity/Quality:

99.5% ^*data from raw suppliers

Squalene-2,3-glycol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Squalene-2,3-glycol is an intermediate in the enzymic conversion of squalene to lanosterol and cholesterol, and a precursor in the chemical synthesis of different squalene oxides.

Technology Process of Squalene-2,3-diol

There total 6 articles about Squalene-2,3-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 14050-42-1,54910-48-4,54910-49-5,54910-50-8,55058-26-9,55058-27-0,132199-42-9,138809-21-9,147731-51-9,7200-26-2,54274-53-2,71606-52-5
2,3-Oxidosqualene

: 14031-37-9
2,3-Dihydroxy-2,3-dihydrosqualene

Guidance literature:: With perchloric acid; In tetrahydrofuran; water; Ambient temperature;

Reference yield:

: 111-02-4
2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene

: 14031-37-9
2,3-Dihydroxy-2,3-dihydrosqualene

Guidance literature:: Multi-step reaction with 3 steps

1: NBS; H₂O / tetrahydrofuran

2: K₂CO₃ / methanol

3: 3 percent aq. HClO₄ / 1,2-dimethoxy-ethane

With N-Bromosuccinimide; perchloric acid; water; potassium carbonate; In tetrahydrofuran; methanol; 1,2-dimethoxyethane; 1: hydroxybromination / 2: Epoxidation / 3: Hydrolysis;
DOI:10.1021/ja993054l

Reference yield:

: 65746-05-6
squalene monobromohydrin: 3-bromo-2,6,10,15,19,23-hexamethyl-6,10,14,18,22-tetracosapentaen-2-ol (all E)

: 14031-37-9
2,3-Dihydroxy-2,3-dihydrosqualene

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / methanol

2: 3 percent aq. HClO₄ / 1,2-dimethoxy-ethane

With perchloric acid; potassium carbonate; In methanol; 1,2-dimethoxyethane; 1: Epoxidation / 2: Hydrolysis;
DOI:10.1021/ja993054l