3-[5-methyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-3-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)-1H-pyrazol-4-yl]-3-phenylacrylamide

Base Information

• Chemical Name: 3-[5-methyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-3-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)-1H-pyrazol-4-yl]-3-phenylacrylamide
• CAS No.: 1000998-51-5
• Molecular Formula: C₁₉H₁₁F₆N₇O₂S₂
• Molecular Weight: 547.464

Synonyms:

Chemical Property of 3-[5-methyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-3-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)-1H-pyrazol-4-yl]-3-phenylacrylamide

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Technology Process of 3-[5-methyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-3-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)-1H-pyrazol-4-yl]-3-phenylacrylamide

There total 1 articles about 3-[5-methyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-3-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)-1H-pyrazol-4-yl]-3-phenylacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

3-methyl-4-phenyl-1H-pyrano[2,3-c]pyrazol-6-one (85094-06-0) + 2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole (53645-98-0) → 3-[5-methyl-1-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yl)-3-(5-trifluoromethyl-[1,3,4]thiadiazol-2-yloxy)-1H-pyrazol-4-yl]-3-phenylacrylamide (1000998-51-5)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1002/jhet.5570440623

upstream raw materials:

3-methyl-4-phenyl-1H-pyrano[2,3-c]pyrazol-6-one

2-chloro-5-(trifluoromethyl)-1,3,4-thiadiazole

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