Chemical Property of Denagliptin
Chemical Property:
- Boiling Point:569.7±50.0 °C(Predicted)
- PKA:7.04±0.37(Predicted)
- PSA：70.12000
- Density:1.33±0.1 g/cm3(Predicted)
- LogP:3.52478
- XLogP3:2.8
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:6
- Rotatable Bond Count:4
- Exact Mass:373.14019669
- Heavy Atom Count:27
- Complexity:542
- Purity/Quality:
-
99% *data from raw suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:
- MSDS Files:
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SDS file from LookChem
Useful:
- Canonical SMILES:C1C(CN(C1C#N)C(=O)C(C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)N)F
- Isomeric SMILES:C1[C@@H](CN([C@@H]1C#N)C(=O)[C@H](C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)N)F
- Recent ClinicalTrials:Study Of GW823093 In Japanese Subjects With Type 2 Diabetes Mellitus
- Recent EU Clinical Trials:“A Multi-Center, Double-Blind, Parallel-Group, Randomized, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of Denagliptin in Subjects With Type 2 Diabetes Mellitus”
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Uses
Treatment of Type 2 diabetes.
