(E)-3-(2-Methylthiazol-4-yl)acrylic acid

Base Information

Chemical Name:(E)-3-(2-Methylthiazol-4-yl)acrylic acid
CAS No.:201142-75-8
Molecular Formula:C₇H₇NO₂S
Molecular Weight:169.204
Hs Code.:
European Community (EC) Number:861-103-1
DSSTox Substance ID:DTXSID00585423
Wikidata:Q72491269
Mol file:201142-75-8.mol

Synonyms:(E)-3-(2-Methylthiazol-4-yl)acrylic acid;201142-75-8;(2E)-3-(2-Methyl-1,3-thiazol-4-yl)prop-2-enoic acid;(2E)-3-(2-methyl-1,3-thiazol-4-yl)acrylic acid;3-(2-methyl-1,3-thiazol-4-yl)prop-2-enoic acid;(E)-3-(2-methyl-1,3-thiazol-4-yl)prop-2-enoic acid;SCHEMBL1124089;DTXSID00585423;XLGMDBLELDJXLS-NSCUHMNNSA-N;MFCD08691273;AKOS008083451;AKOS023502323;3-(2-methyl-thiazol-4-yl)-acrylic acid;(E)-3-(2-Methylthiazol-4-yl)acrylicacid;CS-0282247;EN300-26284;EN300-322093;G46833;A846588;J-500753;2-Propenoic acid, 3-(2-methyl-4-thiazolyl)-, (2E)-;Z221577240;161354-57-0

Suppliers and Price of (E)-3-(2-Methylthiazol-4-yl)acrylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(E)-3-(2-Methylthiazol-4-yl)acrylicacid 95+%
1g
$ 432.00

Chemenu
(E)-3-(2-Methylthiazol-4-yl)acrylicacid 95%
1g
$ 408.00

Alichem
(E)-3-(2-Methylthiazol-4-yl)acrylicacid
1g
$ 366.08

Total 10 raw suppliers

Chemical Property of (E)-3-(2-Methylthiazol-4-yl)acrylic acid

Chemical Property:

Density:1.364
Storage Temp.:2-8°C
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:169.01974964
Heavy Atom Count:11
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

(E)-3-(2-Methylthiazol-4-yl)acrylicacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CS1)C=CC(=O)O
Isomeric SMILES:CC1=NC(=CS1)/C=C/C(=O)O

Technology Process of (E)-3-(2-Methylthiazol-4-yl)acrylic acid

There total 3 articles about (E)-3-(2-Methylthiazol-4-yl)acrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 216318-31-9
(2E)-3-(2-Methylthiazol-4-yl)-2-propenoic acid methyl ester

: 201142-75-8
(2E)-3-(2-methyl-1,3-thiazol-4-yl)prop-2-enoic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; for 3h; Ambient temperature;
DOI:10.1021/ja9823870

Reference yield: 74.0%

: 141-82-2
malonic acid

: 20949-84-2
2-methylthiazole-4-carbaldehyde

: 201142-75-8
(2E)-3-(2-methyl-1,3-thiazol-4-yl)prop-2-enoic acid

Guidance literature:: With piperidine; pyridine; at 100 ℃; for 16h;

Reference yield:

: 20949-84-2
2-methylthiazole-4-carbaldehyde

: 201142-75-8
(2E)-3-(2-methyl-1,3-thiazol-4-yl)prop-2-enoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / benzene / 2 h / Heating

2: 100 percent / aq. LiOH / tetrahydrofuran / 3 h / Ambient temperature

With lithium hydroxide; In tetrahydrofuran; benzene;
DOI:10.1021/ja9823870