4-Chloro-6,7-dimethylquinoline

Base Information

• Chemical Name: 4-Chloro-6,7-dimethylquinoline
• CAS No.: 861038-79-1
• Molecular Formula: C11H10ClN
• Molecular Weight: 191.66
• Hs Code.: 2933499090
• European Community (EC) Number: 804-441-7
• DSSTox Substance ID: DTXSID00589062
• Wikidata: Q82482180
• Mol file: 861038-79-1.mol

Synonyms:4-Chloro-6,7-dimethylquinoline;861038-79-1;SCHEMBL6002911;DTXSID00589062;MFCD09787732;AKOS006281889;AB52102;DB-305787;4-Chloro-6,7-dimethylquinoline, AldrichCPR;CS-0459190

Chemical Property of 4-Chloro-6,7-dimethylquinoline

Chemical Property:

• Vapor Pressure: 0.00211mmHg at 25°C
• Boiling Point: 299.5oC at 760 mmHg
• Flash Point: 163.2oC
• PSA: 12.89000
• Density: 1.188g/cm3
• LogP: 3.50500
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 191.0501770
• Heavy Atom Count: 13
• Complexity: 183

Purity/Quality:

98%min ^*data from raw suppliers

4-Chloro-6,7-dimethylquinoline ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 25-41
• Safety Statements: 26-39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC2=C(C=CN=C2C=C1C)Cl

Technology Process of 4-Chloro-6,7-dimethylquinoline

There total 1 articles about 4-Chloro-6,7-dimethylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-o-xylene (95-64-7) → 4-chloro-6,7-dimethyl-quinoline (861038-79-1)

Guidance literature:

Multi-step reaction with 2 steps

1: bei vermindertem Druck unter Durchleiten von Luft

DOI:10.1021/ja01211a020

Reference yield:

4-chloro-6,7-dimethyl-quinoline (861038-79-1) + 5-diethylamino-2-pentylamine (140-80-7) → N4,N4-diethyl-N1-(6,7-dimethyl-[4]quinolyl)-1-methyl-butanediyldiamine (85438-23-9)

Guidance literature:

at 175 ℃;

DOI:10.1021/ja01211a020

Reference yield:

4-chloro-6,7-dimethyl-quinoline (861038-79-1) + 4-amino-phenol (123-30-8) → 2-diethylaminomethyl-4-(6,7-dimethyl-[4]quinolylamino)-phenol

Guidance literature:

With 1,4-dioxane; Erwaermen des Reaktionsprodukts mit Paraformaldehyd und Diaethylamin in Methanol;

upstream raw materials:

4-amino-o-xylene

Downstream raw materials:

N⁴,N⁴-diethyl-N¹-(6,7-dimethyl-[4]quinolyl)-1-methyl-butanediyldiamine