(S)-(-)-tert-butyl cis-3-[2H₁]-1-phenylprop-2-enyl carbonate

Base Information

• Chemical Name: (S)-(-)-tert-butyl cis-3-[2H₁]-1-phenylprop-2-enyl carbonate
• CAS No.: 1237787-30-2
• Molecular Formula: C₁₄H₁₈O₃
• Molecular Weight: 235.287
• Mol file: 1237787-30-2.mol

Synonyms:

Chemical Property of (S)-(-)-tert-butyl cis-3-[2H₁]-1-phenylprop-2-enyl carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-(-)-tert-butyl cis-3-[2H₁]-1-phenylprop-2-enyl carbonate

There total 1 articles about (S)-(-)-tert-butyl cis-3-[2H₁]-1-phenylprop-2-enyl carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-3-[2H1]-1-phenylprop-2-en-1-ol (914649-61-9) + di-tert-butyl dicarbonate (24424-99-5) → (S)-(-)-tert-butyl cis-3-[2H1]-1-phenylprop-2-enyl carbonate (1237787-30-2)

Guidance literature:

(Z)-3-[2H₁]-1-phenylprop-2-en-1-ol; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; Inert atmosphere;

di-tert-butyl dicarbonate; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/ja105161f

Reference yield:

(S)-(-)-tert-butyl cis-3-[2H1]-1-phenylprop-2-enyl carbonate (1237787-30-2) + Cyclohexylidene-(2-methoxy-ethyl)-amine (13652-41-0) → C15H17(2)HO + C15H17(2)HO + C15H17(2)HO + C15H17(2)HO (1332716-50-3) + C15H17(2)HO (1332716-49-0)

Guidance literature:

Cyclohexylidene-(2-methoxy-ethyl)-amine; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

(S)-(-)-tert-butyl cis-3-[2H₁]-1-phenylprop-2-enyl carbonate; With bis(η3-allyl-μ-chloropalladium(II)); P(p-CH₃OC₆H₄)3; In tetrahydrofuran; at 20 ℃; optical yield given as %ee; regioselective reaction; Further stages; Inert atmosphere;

DOI:10.1021/ja2039503

upstream raw materials:

(Z)-3-[2H₁]-1-phenylprop-2-en-1-ol

di-tert-butyl dicarbonate

Downstream raw materials:

C₁₅H₁₇⁽²⁾HO

C₁₅H₁₇⁽²⁾HO