C₁₆H₂₂O₃

Base Information

• Chemical Name: C₁₆H₂₂O₃
• CAS No.: 1262789-40-1
• Molecular Formula: C₁₆H₂₂O₃
• Molecular Weight: 262.349
• Mol file: 1262789-40-1.mol

Synonyms:

Chemical Property of C₁₆H₂₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₆H₂₂O₃

There total 4 articles about C₁₆H₂₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

C14H20O (1262789-20-7) + lead(IV) tetraacetate (546-67-8) → C16H22O3 (1262789-40-1) + C16H22O3

Guidance literature:

In chloroform; at -40 - 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/ja109925g

Reference yield:

4-methylsalicylaldehyde (698-27-1) → C16H22O3 (1262789-40-1)

Guidance literature:

Multi-step reaction with 4 steps

1: dmap; N-ethyl-N,N-diisopropylamine / dichloromethane / 3 h / Inert atmosphere

2: dimethylsulfide borane complex / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

3: diethyl ether / 1 h / -78 - 20 °C / Inert atmosphere

4: chloroform / 2 h / -40 - 20 °C / Inert atmosphere

With dmap; dimethylsulfide borane complex; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; diethyl ether; dichloromethane; chloroform;

DOI:10.1021/ja109925g

Reference yield:

C13H16O4 (1262789-18-3) → C16H22O3 (1262789-40-1)

Guidance literature:

Multi-step reaction with 3 steps

1: dimethylsulfide borane complex / tetrahydrofuran / 3 h / 0 - 20 °C / Inert atmosphere

2: diethyl ether / 1 h / -78 - 20 °C / Inert atmosphere

3: chloroform / 2 h / -40 - 20 °C / Inert atmosphere

With dimethylsulfide borane complex; In tetrahydrofuran; diethyl ether; chloroform;

DOI:10.1021/ja109925g

upstream raw materials:

C₁₃H₁₈O₄

4-methyl-3-pentenylmagnesium bromide

C₁₄H₂₀O

lead(IV) tetraacetate