3-Chloropyridazine-4-carbonitrile

Base Information

• Chemical Name: 3-Chloropyridazine-4-carbonitrile
• CAS No.: 1445-56-3
• Molecular Formula: C5H2ClN3
• Molecular Weight: 139.5425
• Hs Code.: 2933990090
• European Community (EC) Number: 835-281-6
• DSSTox Substance ID: DTXSID60494820
• Nikkaji Number: J466.162A
• Mol file: 1445-56-3.mol

Synonyms:3-CHLOROPYRIDAZINE-4-CARBONITRILE;1445-56-3;4-Pyridazinecarbonitrile, 3-chloro-;3-Chloro-pyridazine-4-carbonitrile;MFCD11040160;4-cyano-3-chloropyridazine;SCHEMBL9492078;3-chloro-4-pyridazinecarbonitrile;DTXSID60494820;GAQMHKPMJLFJPC-UHFFFAOYSA-N;AKOS006306535;CS-W003747;GS-6388;SB33657;SY012365;FT-0647594;EN300-95014;A884794;J-512334;F2147-1143;Z1198305222

Chemical Property of 3-Chloropyridazine-4-carbonitrile

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 362.935 °C at 760 mmHg
• Flash Point: 173.297 °C
• PSA: 49.57000
• Density: 1.438 g/cm³
• LogP: 1.00168
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 138.9937248
• Heavy Atom Count: 9
• Complexity: 138

Purity/Quality:

97% ^*data from raw suppliers

3-Chloropyridazine-4-carbonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN=NC(=C1C#N)Cl

Technology Process of 3-Chloropyridazine-4-carbonitrile

There total 1 articles about 3-Chloropyridazine-4-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-chloro-4-pyridazinecarbonitrile (1445-56-3)

Guidance literature:

/BRN= 119182/, POCl3, wenig Wasser, 60-70grad;

Reference yield: 80.0%

3-chloro-4-pyridazinecarbonitrile (1445-56-3) + benzylamine (100-46-9) → 3-benzylamino-4-pyridazinecarbonitrile (119581-28-1)

Guidance literature:

In ethanol; for 5h; Heating;

Reference yield: 78.0%

phenylacetylene (536-74-3) + 3-chloro-4-pyridazinecarbonitrile (1445-56-3) → 3-(2-Phenylethinyl)-4-pyridazinecarbonitrile

Guidance literature:

With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; for 7h; Ambient temperature;

DOI:10.1007/BF00809689

Downstream raw materials:

3-phenylamino-4-pyridazinecarbonitrile

3-(2-aminophenylthio)-4-pyridazinecarbonitrile

3-benzylamino-4-pyridazinecarbonitrile

3-Phenoxy-4-pyridazincarbonitril