tetrahydrospectinomycin

Base Information

Chemical Name:tetrahydrospectinomycin
CAS No.:72244-45-2
Molecular Formula:C₃₀H₄₀N₂O₁₁
Molecular Weight:604.654
Hs Code.:
Mol file:72244-45-2.mol

Synonyms:tetrahydrospectinomycin

Suppliers and Price of tetrahydrospectinomycin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of tetrahydrospectinomycin

Chemical Property:

Vapor Pressure:6.79E-27mmHg at 25°C
Boiling Point:798.4°C at 760 mmHg
Flash Point:436.7°C
Density:1.41g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tetrahydrospectinomycin

There total 24 articles about tetrahydrospectinomycin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64979-02-8
N,N'-<(benzyloxy)carbonyl>actinamine

: 64979-14-2,72244-45-2
N,N'-<(benzyloxy)carbonyl>-4(R),4a(R)-tetrahydrospectinomycin

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / silver trifluoromethanesulfonate / tetrahydrofuran / 3 h / -40 °C

2: 1.) sodium metal, 2.) Dowex-50 (H+) / methanol / 1.) 0 deg C, 15 min, 2.) 25 deg C

With Dowex-50 (H+); sodium; silver trifluoromethanesulfonate; In tetrahydrofuran; methanol;
DOI:10.1139/v85-026

Reference yield:

: 21736-83-4
(+)-spectinomycin dihydrochloride

: 64979-14-2,72244-45-2
N,N'-<(benzyloxy)carbonyl>-4(R),4a(R)-tetrahydrospectinomycin

Guidance literature:: Multi-step reaction with 6 steps

1: Dowex-1 (OH-)

2: H₂ / catalytic hydrogenation

3: 97 percent / pyridine / 18 h / 0 °C

4: 9 percent / silver carbonate / acetone; H₂O

5: 62 percent / silver trifluoromethanesulfonate / tetrahydrofuran / 3 h / -40 °C

6: 1.) sodium metal, 2.) Dowex-50 (H+) / methanol / 1.) 0 deg C, 15 min, 2.) 25 deg C

With Dowex-1 (OH-); Dowex-50 (H+); hydrogen; sodium; silver carbonate; silver trifluoromethanesulfonate; In tetrahydrofuran; pyridine; methanol; water; acetone;
DOI:10.1139/v85-026

Reference yield:

: 56733-83-6,58560-43-3,68889-80-5
N,N'-<(benzyloxy)carbonyl>spectinomycin

: 64979-14-2,72244-45-2
N,N'-<(benzyloxy)carbonyl>-4(R),4a(R)-tetrahydrospectinomycin

Guidance literature:: Multi-step reaction with 7 steps

1: 90 percent / H₂ / palladium-on-charcoal / H₂O; propan-2-ol

2: Dowex-1 (OH-)

3: H₂ / catalytic hydrogenation

4: 97 percent / pyridine / 18 h / 0 °C

5: 9 percent / silver carbonate / acetone; H₂O

6: 62 percent / silver trifluoromethanesulfonate / tetrahydrofuran / 3 h / -40 °C

7: 1.) sodium metal, 2.) Dowex-50 (H+) / methanol / 1.) 0 deg C, 15 min, 2.) 25 deg C

With Dowex-1 (OH-); Dowex-50 (H+); hydrogen; sodium; silver carbonate; palladium on activated charcoal; silver trifluoromethanesulfonate; In tetrahydrofuran; pyridine; methanol; water; isopropyl alcohol; acetone;
DOI:10.1139/v85-026