rac-(1R*)-1-Phenyl-2-aminoethanol

Base Information

• Chemical Name: rac-(1R*)-1-Phenyl-2-aminoethanol
• CAS No.: 1936-63-6
• Molecular Formula: C₈H₁₁NO
• Molecular Weight: 137.181
• Mol file: 1936-63-6.mol

Synonyms:

Chemical Property of rac-(1R*)-1-Phenyl-2-aminoethanol

Chemical Property:

• Vapor Pressure: 0.000809mmHg at 25°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of rac-(1R*)-1-Phenyl-2-aminoethanol

There total 259 articles about rac-(1R*)-1-Phenyl-2-aminoethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-aminoacetophenone hydrochloride (5468-37-1) → (S)-2-Amino-1-phenyl-1-ethanol (56613-81-1,1936-63-6)

Guidance literature:

With hydrogen; triethylamine; (2S,4S)-BCPM-rhodium; In methanol; at 50 ℃; for 20h; under 15200 Torr;

DOI:10.1016/S0040-4039(00)95203-1

Reference yield: 99.0%

(S)-2-azido-1-phenylethanol (124817-06-7,18756-01-9) → (S)-2-Amino-1-phenyl-1-ethanol (56613-81-1,1936-63-6)

Guidance literature:

With hydrogen; palladium on activated charcoal; In methanol; at 20 ℃; for 15h;

DOI:10.1016/S0957-4166(02)00322-1

Reference yield: 92.0%

(S)-1-phenyl-2-nitroethanol (149495-00-1) → (S)-2-Amino-1-phenyl-1-ethanol (56613-81-1,1936-63-6)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1039/b904254g

upstream raw materials:

benzoyl cyanide

styrene oxide

N-hydroxy-2-oxo-2-phenylethanimidoyl chloride

2-diazo-acetophenone

Downstream raw materials:

bis-(β-hydroxy-phenethyl)-amine

tris-(β-hydroxy-phenethyl)-amine

piperonal-(β-hydroxy-phenethylimine)

1-(β-hydroxy-phenethylamino)-3-phenoxy-propan-2-ol