3-Hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one

Base Information

Chemical Name:3-Hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one
CAS No.:18088-27-2
Molecular Formula:C19H26O2
Molecular Weight:286.41
Hs Code.:
DSSTox Substance ID:DTXSID00558753
Mol file:18088-27-2.mol

Synonyms:18088-27-2;3-hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one;3-hydroxyandrosta-1,5-dien-17-one;(3beta)-3-Hydroxyandrosta-1,5-dien-17-one;DTXSID00558753;A812569;10,13-dimethyl-3-oxidanyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one

Suppliers and Price of 3-Hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
ANDROSTA-1,5-DIEN-17-ONE, 3 -HYDROXY- (8CI) 95.00%
5G
$ 909.56

Total 7 raw suppliers

Chemical Property of 3-Hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one

Chemical Property:

Refractive Index:1.578
Boiling Point:437.204 °C at 760 mmHg
Flash Point:186.43 °C
PSA：37.30000
Density:1.144 g/cm³
LogP:3.65520
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:286.193280068
Heavy Atom Count:21
Complexity:546

Purity/Quality:

97% ^*data from raw suppliers

ANDROSTA-1,5-DIEN-17-ONE, 3 -HYDROXY- (8CI) 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2=O)CC=C4C3(C=CC(C4)O)C

Technology Process of 3-Hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one

There total 3 articles about 3-Hydroxy-10,13-dimethyl-3,4,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-17-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 16413-85-7
3beta-Acetoxyandrosta-1,5-dien-17-one

: 18088-27-2
3β-hydroxyandrosta-1,5-dien-17-one

Guidance literature:: With potassium carbonate; In methanol; water; at 20 ℃; for 16h;
DOI:10.1016/j.bmc.2006.05.022

Reference yield:

: 2694-94-2
3β-hydroxyandrosta-1,5-dien-17-one 17-ethylene ketal

: 18088-27-2
3β-hydroxyandrosta-1,5-dien-17-one

Guidance literature:: (acid hydrolysis);
DOI:10.1248/cpb.22.2101

Reference yield:

: 571200-68-5
3beta-Acetoxyandrosta-1,5-dien-17-one 17-ethylene ketal

: 18088-27-2
3β-hydroxyandrosta-1,5-dien-17-one

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / p-toluenesulfonic acid / acetone; H₂O / 16 h / 20 °C

2: 83 percent / potassium carbonate / methanol; H₂O / 16 h / 20 °C

With potassium carbonate; toluene-4-sulfonic acid; In methanol; water; acetone;
DOI:10.1016/j.bmc.2006.05.022