3-Methyl-1H-indazole-6-carboxylic acid

Base Information

Chemical Name:3-Methyl-1H-indazole-6-carboxylic acid
CAS No.:201286-96-6
Molecular Formula:C9H8N2O2
Molecular Weight:176.172
Hs Code.:2933990090
Mol file:201286-96-6.mol

Synonyms:3-methyl-indazole-6-carboxylic acid;6-Carboxy-3-methyl-1H-indazole;Y5334;3-methyl-1H-indazole-6-carboxylic acid;

Suppliers and Price of 3-Methyl-1H-indazole-6-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Methyl-1H-indazole-6-carboxylic acid
100mg
$ 155.00

Sigma-Aldrich
3-Methyl-1H-indazole-6-carboxylic acid AldrichCPR
500mg
$ 99.60

J&W Pharmlab
3-Methyl-1H-indazole-6-carboxylic acid 97%
1g
$ 698.00

Crysdot
3-Methyl-1H-indazole-6-carboxylic acid 95+%
5g
$ 1720.00

Crysdot
3-Methyl-1H-indazole-6-carboxylic acid 95+%
1g
$ 598.00

Chemenu
3-Methyl-1H-indazole-6-carboxylic acid 95%
1g
$ 356.00

American Custom Chemicals Corporation
3-METHYL-1H-INDAZOLE-6-CARBOXYLIC ACID 95.00%
5G
$ 909.56

Alichem
3-Methyl-1H-indazole-6-carboxylic acid
1g
$ 311.08

Total 18 raw suppliers

Chemical Property of 3-Methyl-1H-indazole-6-carboxylic acid

Chemical Property:

Boiling Point:439.112 °C at 760 mmHg
Flash Point:219.368 °C
PSA：65.98000
Density:1.422 g/cm³
LogP:1.56950
Storage Temp.:2-8°C

Purity/Quality:

97% ^*data from raw suppliers

3-Methyl-1H-indazole-6-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-Methyl-1H-indazole-6-carboxylic acid

There total 9 articles about 3-Methyl-1H-indazole-6-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 201286-97-7
methyl 3-methyl-1-[(trifluoromethyl)sulfonyl]-1H-indazole-6-carboxylate

: 201286-96-6
3-methyl-indazole-6-carboxylic acid

Guidance literature:: methyl 3-methyl-1-[(trifluoromethyl)sulfonyl]-1H-indazole-6-carboxylate; With water; potassium carbonate; In methanol; for 2h; Heating / reflux;

With potassium hydrogensulfate; In water; pH=3 - 3.5;

Reference yield: 17.0%

: 540-80-7
tert.-butylnitrite

: 5129-23-7
3-Amino-4-ethyl benzoic acid

: 201286-96-6
3-methyl-indazole-6-carboxylic acid

Guidance literature:: 3-Amino-4-ethyl benzoic acid; With boron trifluoride diethyl etherate; In tetrahydrofuran; chloroform; at -12 ℃; for 0.333333h;

tert.-butylnitrite; In tetrahydrofuran; chloroform; at 5 ℃; for 1.5h;

With potassium acetate; 18-crown-6 ether; In tetrahydrofuran; chloroform; at 20 ℃; for 40h;

Reference yield:

: 201286-98-8
3-methyl-1-[(trifluoromethyl)sulfonyl]-1H-indazol-6-yl trifluoromethanesulfonate

: 201286-96-6
3-methyl-indazole-6-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate / N,N-dimethyl-formamide / 48 h / 20 °C / 760.05 Torr

2.1: water; potassium carbonate / methanol / 2 h / Heating / reflux

2.2: pH 3 - 3.5

With water; potassium carbonate; triethylamine; 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; In methanol; N,N-dimethyl-formamide;