Technology Process of Ni(II) 5-p-tolyl-10-(2-formylvinyl)-2,3,7,8,12,13,17,18-octaethylporphyrin
There total 1 articles about Ni(II) 5-p-tolyl-10-(2-formylvinyl)-2,3,7,8,12,13,17,18-octaethylporphyrin which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
trichlorophosphate;
In
1,2-dichloro-ethane;
dropwise addn. of POCl3 to aldehyde soln., stirring at 50°C for 30 min., addn. of porphyrin soln., stirring at 50°C for 4 h (N2); addn. of satd. aq. NaOAc, stirring 4 h, pouring into water, extn. (CHCl3), washing (water), drying (Na2SO4), evapn. (rotary evaporator), column chromy. (silica gel, benzene, twice), evapn., recrystn. (CH2Cl2-MeOH);
DOI:10.1246/bcsj.65.3322
- Guidance literature:
-
In
trifluoroacetic acid;
dissolution of porphyrin in trifluoroacetic acid, stirring 2 h; pouring into water, extn. (CH2Cl2), washing (water, satd. aq. NaHCO3, water), drying (Na2SO4), evapn., column chromy. (silica gel, benzene), evapn., recrystn. (CH2Cl2-hexane), total yield 66%, isomer ratio >95:5;
DOI:10.1246/bcsj.65.3322
