Technology Process of C35H49N3O5
There total 25 articles about C35H49N3O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 10 steps
1: n-BuLi / -78 °C
2: Dess-Martin periodinane; NaHCO3 / 0 - 20 °C
3: 96 percent / i-Pr2NEt; LiCl / acetonitrile / 20 °C
4: 92 percent / AD-mix α; MeSO2NH2; NaHCO3 / 2-methyl-propan-2-ol; H2O / 0 °C
5: 95 percent / PPTS / CH2Cl2 / 0 - 20 °C
6: K-selectride / tetrahydrofuran / -78 °C
7: NaHMDS / tetrahydrofuran; dimethylformamide / 0 °C
8: TBAF / tetrahydrofuran / 0 - 20 °C
9: Et3N / CH2Cl2 / 0 °C
10: NaN3 / dimethylformamide / 90 °C
With
AD-mix-α; n-butyllithium; sodium azide; methanesulfonamide; tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; sodium hydrogencarbonate; potassium tri-sec-butyl-borohydride; Dess-Martin periodane; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;
4: Sharpless asymmetric dihydroxylation;
DOI:10.1055/s-2007-985585
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 96 percent / i-Pr2NEt; LiCl / acetonitrile / 20 °C
2: 92 percent / AD-mix α; MeSO2NH2; NaHCO3 / 2-methyl-propan-2-ol; H2O / 0 °C
3: 95 percent / PPTS / CH2Cl2 / 0 - 20 °C
4: K-selectride / tetrahydrofuran / -78 °C
5: NaHMDS / tetrahydrofuran; dimethylformamide / 0 °C
6: TBAF / tetrahydrofuran / 0 - 20 °C
7: Et3N / CH2Cl2 / 0 °C
8: NaN3 / dimethylformamide / 90 °C
With
AD-mix-α; sodium azide; methanesulfonamide; tetrabutyl ammonium fluoride; sodium hexamethyldisilazane; pyridinium p-toluenesulfonate; sodium hydrogencarbonate; potassium tri-sec-butyl-borohydride; triethylamine; N-ethyl-N,N-diisopropylamine; lithium chloride;
In
tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; acetonitrile; tert-butyl alcohol;
2: Sharpless asymmetric dihydroxylation;
DOI:10.1055/s-2007-985585