Technology Process of C16H18O
There total 4 articles about C16H18O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Dess-Martin periodane;
In
dichloromethane;
at 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ja4025963
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
1.2: 20 h / 20 °C / Inert atmosphere
2.1: diisobutylaluminium hydride / toluene / 4 h / -78 - 0 °C / Inert atmosphere
3.1: zinc; ammonium chloride / toluene; water; tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
4.1: Dess-Martin periodane / dichloromethane / 3 h / 20 °C / Inert atmosphere
With
diisobutylaluminium hydride; ammonium chloride; Dess-Martin periodane; zinc; lithium diisopropyl amide;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1021/ja4025963
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diisobutylaluminium hydride / toluene / 4 h / -78 - 0 °C / Inert atmosphere
2: zinc; ammonium chloride / toluene; water; tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
3: Dess-Martin periodane / dichloromethane / 3 h / 20 °C / Inert atmosphere
With
diisobutylaluminium hydride; ammonium chloride; Dess-Martin periodane; zinc;
In
tetrahydrofuran; dichloromethane; water; toluene;
DOI:10.1021/ja4025963
