6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

Base Information

Chemical Name:6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide
CAS No.:1041853-24-0
Molecular Formula:C10H7 Br Cl N3 O2
Molecular Weight:316.541
Hs Code.:
Mol file:1041853-24-0.mol

Synonyms:

Suppliers and Price of 6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynChem
6-Bromo-4-chloro-7-methoxycinnoline-3-carboxylic acid amide 95+%
5 g
$ 1185.00

SynChem
6-Bromo-4-chloro-7-methoxycinnoline-3-carboxylic acid amide 95+%
1 g
$ 295.00

Total 6 raw suppliers

Chemical Property of 6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

Chemical Property:

PSA：79.09000
LogP:3.03740

Purity/Quality:

98%min ^*data from raw suppliers

6-Bromo-4-chloro-7-methoxycinnoline-3-carboxylic acid amide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

There total 5 articles about 6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 1041853-21-7
6-bromo-4-hydroxy-7-methoxycinnoline-3-carboxylic acid

: 1041853-24-0
6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

Guidance literature:: 6-bromo-4-hydroxy-7-methoxycinnoline-3-carboxylic acid; With thionyl chloride; N,N-dimethyl-formamide; for 4h; Heating / reflux;

With ammonia; In water; acetone; at 0 ℃; for 0.25h;

Reference yield:

: 1041853-18-2
4-amino-6-bromo-7-methoxycinnoline-3-carboxamide

: 1041853-24-0
6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide / ethanol; water / Reflux

2.1: thionyl chloride; N,N-dimethyl-formamide / Reflux

2.2: 0 °C

With thionyl chloride; N,N-dimethyl-formamide; potassium hydroxide; In ethanol; water;
DOI:10.1016/j.bmcl.2011.01.033

Reference yield:

: 19056-40-7
4-bromo-3-methoxyaniline

: 1041853-24-0
6-bromo-4-chloro-7-methoxycinnoline-3-carboxamide

Guidance literature:: Multi-step reaction with 4 steps

1.1: hydrogenchloride; sodium nitrite / water / 0 °C

1.2: 20 °C

2.1: titanium tetrachloride / toluene / Reflux

3.1: potassium hydroxide / ethanol; water / Reflux

4.1: thionyl chloride; N,N-dimethyl-formamide / Reflux

4.2: 0 °C

With hydrogenchloride; thionyl chloride; titanium tetrachloride; N,N-dimethyl-formamide; potassium hydroxide; sodium nitrite; In ethanol; water; toluene;
DOI:10.1016/j.bmcl.2011.01.033