2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-

Base Information

Chemical Name:2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-
CAS No.:1093978-89-2
Molecular Formula:C25H22F4N6O2
Molecular Weight:514.47
Hs Code.:
Mol file:1093978-89-2.mol

2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-

Synonyms:6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one;2H-1-benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-;2H-1-Benzazepin-2-one 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-;

Suppliers and Price of 2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
gamma-secretasemodulator2 98+%
10mg
$ 394.00

Crysdot
gamma-secretasemodulator2 98+%
50mg
$ 859.00

ChemScene
gamma-secretasemodulator2 98.59%
10mg
$ 550.00

ChemScene
gamma-secretasemodulator2 98.59%
50mg
$ 1200.00

Chemenu
6-fluoro-3-(4-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one 98%
50mg
$ 803.00

Chemenu
6-fluoro-3-(4-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-1H-1,2,3-triazol-1-yl)-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one 98%
10mg
$ 368.00

American Custom Chemicals Corporation
6-FLUORO-3-(4-(3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL)-1H-1,2,3-TRIAZOL-1-YL)-1-(2,2,2-TRIFLUOROETHYL)-4,5-DIHYDRO-1H-BENZO[B]AZEPIN-2(3H)-ONE 95.00%
10MG
$ 1012.20

AK Scientific
6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-benzazepin-2-one
2mg
$ 129.00

Total 16 raw suppliers

Chemical Property of 2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-

Chemical Property:

Boiling Point:729.8 °C at 760 mmHg
PKA:5.34±0.61(Predicted)
Flash Point:395.2 °C
PSA：78.07000
Density:1.43 g/cm³
LogP:4.73470

Purity/Quality:

97% ^*data from raw suppliers

gamma-secretasemodulator2 98+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-benzazepin-2-one can treat Alzheirmer’s disease and related conditions.

Technology Process of 2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)-

There total 1 articles about 2H-1-BENZAZEPIN-2-ONE 6-FLUORO-1,3,4,5-TETRAHYDRO-3-[4-[3-METHOXY-4-(4-METHYL-1H-IMIDAZOL-1-YL)PHENYL]-1H-1,2,3-TRIAZOL-1-YL]-1-(2,2,2-TRIFLUOROETHYL)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6226-25-1
2,2,2-trifluoroethyl trifluoromethanesulphonate

: 1093978-67-6
6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

: 1093978-89-2
6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1-(2,2,2-trifluoroethyl)-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one

Guidance literature:: 6-fluoro-3-{4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl}-1,3,4,5-tetrahydro-2H-1-benzazepin-2-one; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

2,2,2-trifluoroethyl trifluoromethanesulphonate; In N,N-dimethyl-formamide; mineral oil; at 20 ℃;