(1'S,2R,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine

Base Information

• Chemical Name: (1'S,2R,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine
• CAS No.: 1448848-41-6
• Molecular Formula: C₃₂H₃₈N₂O₅
• Molecular Weight: 530.664
• Mol file: 1448848-41-6.mol

Synonyms:

Chemical Property of (1'S,2R,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1'S,2R,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine

There total 1 articles about (1'S,2R,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

(S,E)-N,N-dibenzyl-4-nitro-1-phenylbut-3-en-2-amine (1448848-38-1) + ethyl vinyl ether (109-92-2,25104-37-4) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → (1'S,2R,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine (1448848-41-6) + (1'S,2S,3aR,4R,6S)-4-(1'-N,N-dibenzylamino-2'-phenylethyl)-6-ethoxy-2-methoxycarbonylperhydro-isoxazolidino[2,3-b]-1,2-oxazine (1448848-42-7)

Guidance literature:

With lithium perchlorate; In tetrahydrofuran; water; at 25 ℃; for 72h; Solvent; Reagent/catalyst; Time; diastereoselective reaction; Sealed tube;

DOI:10.3762/bjoc.9.96

upstream raw materials:

(S,E)-N,N-dibenzyl-4-nitro-1-phenylbut-3-en-2-amine

ethyl vinyl ether

acrylic acid methyl ester