Cyclobutylhydrazine dihydrochloride

Base Information

• Chemical Name: Cyclobutylhydrazine dihydrochloride
• CAS No.: 1156980-49-2
• Molecular Formula: C4H12Cl2N2
• Molecular Weight: 159.05700
• Hs Code.: 2928000090
• European Community (EC) Number: 818-204-0
• DSSTox Substance ID: DTXSID30656019
• Mol file: 1156980-49-2.mol

Synonyms:cyclobutylhydrazine dihydrochloride;1156980-49-2;1-cyclobutylhydrazine dihydrochloride;cyclobutylhydrazine;dihydrochloride;MFCD09834105;1-CYCLOBUTYLHYDRAZINE 2HCL;cyclobutyldiazane dihydrochloride;SCHEMBL1740316;cyclobutylhydrazinedihydrochloride;DTXSID30656019;UAVGQVJTQZESRT-UHFFFAOYSA-N;AM9783;AKOS015918974;GS-2512;SB13111;BL010353;CS-0054590;FT-0659332;Cyclobutylhydrazine--hydrogen chloride (1/2);EN300-29515;Hydrazine, cyclobutyl-, hydrochloride (1:2);A803475

Chemical Property of Cyclobutylhydrazine dihydrochloride

Chemical Property:

• PSA: 38.05000
• LogP: 2.69740
• Storage Temp.: Sealed in dry,Room Temperature
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 158.0377538
• Heavy Atom Count: 8
• Complexity: 40.8

Purity/Quality:

97% ^*data from raw suppliers

CyclobutylhydrazineDihydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(C1)NN.Cl.Cl

Technology Process of Cyclobutylhydrazine dihydrochloride

There total 2 articles about Cyclobutylhydrazine dihydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyl 2-cyclobutylidenehydrazinecarboxylate (158001-20-8) → cyclobutyl hydrazine hydrochloride (1156980-49-2,158001-21-9)

Guidance literature:

tert-butyl 2-cyclobutylidenehydrazinecarboxylate; With sodium cyanoborohydride; In tetrahydrofuran; methanol; for 0.833333h; Heating / reflux;

With hydrogenchloride; In tetrahydrofuran; methanol; water; for 0.5h; Heating / reflux;

Reference yield:

→ cyclobutyl hydrazine hydrochloride (1156980-49-2,158001-21-9)

Guidance literature:

Reference yield: 86.0%

4-acetyl-2-((benzyloxy)methyl)-5-chloropyridazin-3(2H)-one + cyclobutyl hydrazine hydrochloride (1156980-49-2,158001-21-9) → 5-((benzyloxy)methyl)-1-cyclobutyl-3-methyl-1,5-dihydro-4H-pyrazolo[3,4-d]pyridazin-4-one

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at -10 - 0 ℃; for 2.5h;

upstream raw materials:

tert-butyl 2-cyclobutylidenehydrazinecarboxylate

Downstream raw materials:

1-cyclobutyl-3-methyl-1H-pyrazol-5-amine